STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argHArgininosuccinate lyase; Catalyzes the formation of arginine from(N-L-arginino)succinate; Orthologue of BL1057. (511 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; Orthologue of BL1058; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.999
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.990
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 0.988
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.986
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.967
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.944
argD
COG family: PLP-dependentaminotransferases; Orthologue of BL1061; PFAM_ID: aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.922
purB
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novosynthesis of purines: the cleavage of adenylosuccinate andsuccinylaminoimidazole carboxamide ribotide; Orthologue of BL1800.
    
 0.910
gltA2
COG family: citrate synthase; Orthologue of BL1733; Belongs to the citrate synthase family.
    
 0.909
icd1
COG family: isocitrate dehydrogenases; Orthologue of BL1499; Oxalosuccinate decarboxylase; PFAM_ID: isodh; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
     
 0.908
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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