STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABN56046.1Cysteate synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. (430 aa)    
Predicted Functional Partners:
ABN56047.1
Sulfopyruvate decarboxylase subunit beta / sulfopyruvate decarboxylase subunit alpha; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mhu:Mhun_2976 thiamine pyrophosphate enzyme-like TPP-binding.
 
   
 0.970
ABN56044.1
PFAM: Fe-S cluster domain protein; KEGG: mhu:Mhun_2979 putative Fe-S cluster.
 
     0.967
ABN56043.1
PFAM: cobalamin synthesis protein, P47K; SMART: AAA ATPase; KEGG: mhu:Mhun_2980 cobalamin synthesis protein, P47K.
 
     0.965
ABN56045.1
Protein of unknown function DUF39; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF39; KEGG: mhu:Mhun_2978 protein of unknown function DUF39.
 
   
 0.957
ABN56904.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: mhu:Mhun_2292 homoserine dehydrogenase.
 
 
 0.923
ABN56042.1
ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mhu:Mhun_2981 ABC transporter related.
 
     0.882
ABN56156.1
KEGG: mhu:Mhun_3054 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
 
 
 0.840
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.755
ABN56568.1
TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit.
  
  
 0.718
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
  
 0.718
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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