STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (240 aa)    
Predicted Functional Partners:
psmB
Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
ABN57604.1
PFAM: Shwachman-Bodian-Diamond syndrome proteins; KEGG: mhu:Mhun_2283 protein of unknown function UPF0023.
 
    0.989
rpl15e
PFAM: Ribosomal protein L15e; KEGG: mhu:Mhun_2279 ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
  
 0.980
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
 
 0.966
ABN57238.1
Proteasome-activating nucleotidase; KEGG: mhu:Mhun_1040 26S proteasome subunit P45 family; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
 
 0.962
ABN58220.1
Proteasome Rpn11 subunit JAMM motif, Metallo peptidase, MEROPS family M67B; KEGG: mhu:Mhun_2403 hypothetical protein.
   
 0.961
rnp2
Ribonuclease P-related protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
  
    0.959
rnp3
Ribonuclease P protein subunit Rpp30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
   0.959
rpl37ae
LSU ribosomal protein L37AE; Binds to the 23S rRNA.
 
    0.957
rpl40e
PFAM: Ribosomal protein L40e; KEGG: mhu:Mhun_2870 ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.912
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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