STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0093AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (520 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.948
Tpen_1815
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mka:MK0089 CBS-domain-containing protein.
  
  
 0.820
Tpen_0309
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: sto:ST0343 hypothetical cleavage and polyadenylation specificity factor large subunit.
 
     0.743
Tpen_0047
PFAM: phosphoribosyltransferase; KEGG: pai:PAE1598 uracil phosphoribosyltransferase.
  
  
 0.734
Tpen_0384
Ribose 1,5-bisphosphate isomerase; KEGG: tko:TK0185 translation initiation factor eIF-2B, delta subunit; TIGRFAM: putative translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized proteins; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
 0.681
Tpen_0386
KEGG: mca:MCA1716 ribose-phosphate pyrophosphokinase family protein; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
 
   
 0.681
Tpen_0092
KEGG: sso:SSO0205 hypothetical protein.
       0.636
Tpen_0094
PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: pai:PAE3427 aldehyde ferredoxin oxidoreductase (aor).
     
 0.626
Tpen_1466
PFAM: UspA domain protein; KEGG: sto:ST1524 hypothetical protein.
  
    0.623
Tpen_0091
3-octaprenyl-4hydroxybenzoate decarboxylase; KEGG: mta:Moth_0095 carboxylyase-related protein.
       0.619
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
Server load: high (82%) [HD]