node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tpen_0707 | Tpen_0709 | Tpen_0707 | Tpen_0709 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.819 |
Tpen_0707 | hflX | Tpen_0707 | Tpen_0708 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.872 |
Tpen_0707 | rpl11 | Tpen_0707 | Tpen_0224 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.717 |
Tpen_0707 | rpl13 | Tpen_0707 | Tpen_0278 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.798 |
Tpen_0707 | rpl2 | Tpen_0707 | Tpen_0227 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.789 |
Tpen_0707 | rpl22 | Tpen_0707 | Tpen_0489 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.748 |
Tpen_0707 | rpl24 | Tpen_0707 | Tpen_0244 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.795 |
Tpen_0707 | rpl3 | Tpen_0707 | Tpen_0230 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.769 |
Tpen_0707 | rpl5 | Tpen_0707 | Tpen_0242 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.768 |
Tpen_0707 | rps9 | Tpen_0707 | Tpen_0277 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | PFAM: ribosomal protein S9; KEGG: afu:AF1129 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.768 |
Tpen_0709 | Tpen_0707 | Tpen_0709 | Tpen_0707 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | 0.819 |
Tpen_0709 | hflX | Tpen_0709 | Tpen_0708 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.852 |
hflX | Tpen_0707 | Tpen_0708 | Tpen_0707 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | 0.872 |
hflX | Tpen_0709 | Tpen_0708 | Tpen_0709 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.852 |
hflX | rpl11 | Tpen_0708 | Tpen_0224 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.893 |
hflX | rpl13 | Tpen_0708 | Tpen_0278 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.870 |
hflX | rpl2 | Tpen_0708 | Tpen_0227 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.849 |
hflX | rpl22 | Tpen_0708 | Tpen_0489 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.864 |
hflX | rpl24 | Tpen_0708 | Tpen_0244 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.837 |
hflX | rpl3 | Tpen_0708 | Tpen_0230 | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.885 |