STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0863Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I. (281 aa)    
Predicted Functional Partners:
Tpen_0292
Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I.
  
  
 
0.900
Tpen_0864
Peptidase M50; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: pfu:PF0167 metalloprotease.
 
  
 0.800
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.715
Tpen_0338
PFAM: H+-transporting two-sector ATPase, C subunit; KEGG: noc:Noc_2086 H+-transporting two-sector ATPase, C subunit; Belongs to the V-ATPase proteolipid subunit family.
    
 0.664
Tpen_0340
TIGRFAM: V-type ATPase, D subunit; KEGG: nph:NP0264A H(+)-transporting two-sector ATPase subunit D.a (A-type ATP synthase).
 
  
  0.646
lig1
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
  
 0.633
Tpen_0339
Hypothetical protein.
    
 0.606
atpE
H+-transporting two-sector ATPase, E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
 0.588
lig2
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
    
 0.586
atpB
Sodium-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
  
 
  0.577
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.