STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surE5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (260 aa)    
Predicted Functional Partners:
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.936
Tpen_1064
PFAM: IMP dehydrogenase/GMP reductase; 2-nitropropane dioxygenase, NPD; KEGG: pub:SAR11_0649 IMP dehydrogenase-like protein.
    
 0.935
Tpen_0948
Thymidylate synthase-like protein; KEGG: mac:MA4543 thymidylate synthase.
 
 
 0.932
Tpen_1147
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mka:MK0735 orotidine-5'-phosphate decarboxylase.
    
 0.929
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.920
Tpen_0142
Exopolyphosphatase / 3'-nucleotidase / 5'-nucleotidase; KEGG: tma:TM1662 acid phosphatase; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE.
  
  
 
0.920
adk-2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.920
Tpen_0047
PFAM: phosphoribosyltransferase; KEGG: pai:PAE1598 uracil phosphoribosyltransferase.
    
 0.918
Tpen_1102
PFAM: phosphoribosyltransferase; KEGG: hwa:HQ3228A purine phosphoribosyltransferase 2 (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase).
    
 0.917
Tpen_1380
Hypothetical protein; KEGG: tko:TK1489 adenine phosphoribosyltransferase.
    
 0.917
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.