STRINGSTRING
holE protein (Wigglesworthia glossinidia Gb) - STRING interaction network
"holE" - DNA polymerase III subunit theta in Wigglesworthia glossinidia Gb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holEDNA polymerase III subunit theta (76 aa)    
Predicted Functional Partners:
dnaE
Hypothetical protein (1159 aa)
       
  0.999
dnaQ
Hypothetical protein (246 aa)
     
  0.992
ndk
Hypothetical protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (142 aa)
         
    0.900
dcd
Deoxycytidine triphosphate deaminase (196 aa)
         
    0.900
pykA
Hypothetical protein (479 aa)
         
    0.900
holA
Hypothetical protein (347 aa)
   
 
    0.891
holB
Hypothetical protein (329 aa)
       
  0.887
dnaX
Hypothetical protein (365 aa)
       
  0.882
dnaN
Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (369 aa)
       
    0.829
polA
Hypothetical protein (289 aa)
         
    0.800
Your Current Organism:
Wigglesworthia glossinidia Gb
NCBI taxonomy Id: 36870
Other names: Glossina brevipalpis P-endosymbiont, W. glossinidia endosymbiont of Glossina brevipalpis, Wigglesworthia brevipalpis, Wigglesworthia glossinidia Gb, Wigglesworthia glossinidia brevipalpis, Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Server load: low (16%) [HD]