STRINGSTRING
dapE protein (Wigglesworthia glossinidia Gb) - STRING interaction network
"dapE" - Succinyl-diaminopimelate desuccinylase in Wigglesworthia glossinidia Gb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (376 aa)    
Predicted Functional Partners:
dapF
Hypothetical protein; Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (276 aa)
       
  0.998
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (361 aa)
       
  0.922
dapD
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase (274 aa)
 
   
  0.911
bioA
Hypothetical protein (433 aa)
   
 
  0.876
deaD
Hypothetical protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation (583 aa)
   
 
  0.875
glyA
Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (420 aa)
   
 
  0.870
thiD
Hypothetical protein (272 aa)
         
  0.868
rplU
Hypothetical protein; This protein binds to 23S rRNA in the presence of protein L20 (103 aa)
       
    0.868
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (337 aa)
   
 
    0.865
pyrB
Hypothetical protein (309 aa)
       
  0.859
Your Current Organism:
Wigglesworthia glossinidia Gb
NCBI taxonomy Id: 36870
Other names: Glossina brevipalpis P-endosymbiont, W. glossinidia endosymbiont of Glossina brevipalpis, Wigglesworthia brevipalpis, Wigglesworthia glossinidia Gb, Wigglesworthia glossinidia brevipalpis, Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Server load: low (10%) [HD]