STRINGSTRING
pyrF protein (Wigglesworthia glossinidia Gb) - STRING interaction network
"pyrF" - Hypothetical protein in Wigglesworthia glossinidia Gb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFHypothetical protein; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP) (232 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (217 aa)
   
  0.999
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (337 aa)
   
  0.998
pyrB
Hypothetical protein (309 aa)
   
 
  0.995
carB
Hypothetical protein (1084 aa)
   
  0.994
pyrH
Hypothetical protein; Catalyzes the reversible phosphorylation of UMP to UDP (241 aa)
   
 
  0.994
cmk
Hypothetical protein (186 aa)
   
 
    0.993
carA
Carbamoyl phosphate synthase small subunit (376 aa)
   
 
  0.975
thrA
Hypothetical protein (815 aa)
   
 
  0.934
surE
Hypothetical protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5’- monophosphates and ribonucleoside 3’-monophosphates with highest affinity to 3’-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3’-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (250 aa)
   
 
    0.902
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (522 aa)
   
   
  0.883
Your Current Organism:
Wigglesworthia glossinidia Gb
NCBI taxonomy Id: 36870
Other names: Glossina brevipalpis P-endosymbiont, W. glossinidia endosymbiont of Glossina brevipalpis, Wigglesworthia brevipalpis, Wigglesworthia glossinidia Gb, Wigglesworthia glossinidia brevipalpis, Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Server load: low (15%) [HD]