STRINGSTRING
tsaC protein (Wigglesworthia glossinidia Gb) - STRING interaction network
"tsaC" - Hypothetical protein in Wigglesworthia glossinidia Gb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaCHypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate (194 aa)    
Predicted Functional Partners:
tsaD
Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (340 aa)
 
 
  0.967
coaD
Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4’- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (168 aa)
         
  0.835
gltX
Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (473 aa)
   
   
  0.819
def
Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (152 aa)
   
   
  0.769
fmt
Hypothetical protein; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (319 aa)
 
   
  0.729
trxA
Hypothetical protein (112 aa)
   
   
  0.717
hemC
Hypothetical protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (291 aa)
           
  0.714
prfA
Hypothetical protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (364 aa)
   
   
  0.709
truA
Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (264 aa)
   
   
  0.700
hemD
Hypothetical protein (245 aa)
     
   
  0.697
Your Current Organism:
Wigglesworthia glossinidia Gb
NCBI taxonomy Id: 36870
Other names: Glossina brevipalpis P-endosymbiont, W. glossinidia endosymbiont of Glossina brevipalpis, Wigglesworthia brevipalpis, Wigglesworthia glossinidia Gb, Wigglesworthia glossinidia brevipalpis, Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Server load: low (9%) [HD]