Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (160 aa)
Predicted Functional Partners:
Thioredoxin-related family protein (207 aa)
Uncharacterized protein; Belongs to the precorrin methyltransferase family (373 aa)
Uncharacterized protein (331 aa)
Ubiquitin-associated domain-containing family protein (414 aa)
Ubiquitin-associated domain-containing family protein (315 aa)
Ubiquitin-associated domain-containing family protein (415 aa)
Ribose 5-phosphate isomerase-related family protein (285 aa)
Uncharacterized protein (197 aa)
annotation not available (108 aa)
annotation not available (184 aa)
Your Current Organism:
NCBI taxonomy Id: 3694 Other names: P. trichocarpa, Populus balsamifera subsp. trichocarpa, Populus balsamifera subsp. trichocarpa (Torr. & A.Gray) Brayshaw, Populus trichocarpa, Populus trichocarpa Torr. & A.Gray, black cottonwood, western balsam poplar