Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Predicted protein (273 aa)
Predicted Functional Partners:
Hypothetical protein (205 aa)
Predicted protein (358 aa)
Predicted protein (97 aa)
Uncharacterized protein (121 aa)
Uncharacterized protein (317 aa)
Uncharacterized protein (109 aa)
Predicted protein (409 aa)
Uncharacterized protein (124 aa)
Predicted protein (104 aa)
Uncharacterized protein (116 aa)
Your Current Organism:
NCBI taxonomy Id: 3694 Other names: Balanopales, Euphorbiales, Flacourtiaceae, Linales, Malpighiales, P. trichocarpa, Populus, Populus L., Populus balsamifera subsp. trichocarpa, Populus balsamifera subsp. trichocarpa (Torr. et A.Gray) Brayshaw, Populus trichocarpa, Populus trichocarpa Torr. & A.Gray, Populus trichocarpa Torr. et A.Gray, Rhizophorales, Salicaceae, Saliceae, Violales, Violanae, black cottonwood, poplar, poplar trees, poplars, western balsam poplar, willow family