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DHFR-TS-2 protein (Populus trichocarpa) - STRING interaction network
"DHFR-TS-2" - Bifunctional dihydrofolate reductase-thymidylate synthase in Populus trichocarpa
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHFR-TS-2Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (528 aa)    
Predicted Functional Partners:
POPTR_0001s36370.1
Thymidylate kinase family protein (222 aa)
   
 
  0.998
POPTR_0015s10850.1
Cytidine/deoxycytidylate deaminase family protein; Putative uncharacterized protein [source-UniProtKB/TrEMBL;Acc-A9PBQ9_POPTR] (229 aa)
   
  0.997
POPTR_0012s09980.1
Cytidine/deoxycytidylate deaminase family protein (225 aa)
   
  0.997
POPTR_0018s08720.1
Uncharacterized protein (121 aa)
   
  0.994
POPTR_0014s18160.1
Uncharacterized protein (58 aa)
   
  0.994
POPTR_0014s18070.1
annotation not available (54 aa)
   
  0.994
POPTR_0280s00200.1
annotation not available (97 aa)
   
 
  0.992
POPTR_0016s01130.1
annotation not available (173 aa)
   
 
  0.992
POPTR_0006s01690.1
Thymidine kinase (279 aa)
   
 
  0.992
POPTR_0002s22130.1
Thymidine kinase (210 aa)
   
 
  0.992
Your Current Organism:
Populus trichocarpa
NCBI taxonomy Id: 3694
Other names: P. trichocarpa, Populus balsamifera subsp. trichocarpa, Populus balsamifera subsp. trichocarpa (Torr. & A.Gray) Brayshaw, Populus trichocarpa, Populus trichocarpa Torr. & A.Gray, black cottonwood, western balsam poplar
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