STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)    
Predicted Functional Partners:
ABP53176.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.964
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.961
ABP55594.1
PFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.945
ABP54587.1
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.940
ABP56225.1
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
    
 0.929
ABP55860.1
TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family.
     
 0.927
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.915
ABP52908.1
PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.914
ABP53175.1
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
   
 
 0.862
ABP52592.1
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein.
   
 
 0.860
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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