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CYP703A2 protein (Arabidopsis thaliana) - STRING interaction network
"CYP703A2" - Cytochrome P450, family 703, subfamily A, polypeptide 2 in Arabidopsis thaliana
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Predicted Interactions
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textmining
co-expression
protein homology
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CYP703A2Cytochrome P450, family 703, subfamily A, polypeptide 2; Involved in pollen wall development. Catalyzes the conversion of medium-chain saturated fatty acids to the corresponding monohydroxylated fatty acids, with a preferential hydroxylation of lauric acid at the C-7 position. In-chain hydroxylated fatty acids, together with omega-hydroxylated fatty acids, are key monomeric aliphatic building blocks for sporopollenin synthesis during exine formation; Belongs to the cytochrome P450 family (510 aa)    
Predicted Functional Partners:
ACOS5
4-coumarate--CoA ligase-like 1; Encodes an acyl-CoA synthetase, has in vitro activity towards medium- to long-chain fatty acids and their hydroxylated derivatives. Expressed in the tapetum. Involved in pollen wall exine formation. Null mutants were devoid of pollen grains at anther maturity and were completely male sterile; Belongs to the ATP-dependent AMP-binding enzyme family (542 aa)
     
   
  0.980
LAP5
Chalcone and stilbene synthase family protein; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v-hydroxylated fatty acyl-CoAs (e.g. 12- hydroxyoctadecano [...] (392 aa)
     
   
  0.959
LAP6
Chalcone and stilbene synthase family protein; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v-hydroxylated fatty acyl-CoAs (e.g. 12- hydroxyoctadecano [...] (395 aa)
     
   
  0.955
FAR2
Jojoba acyl CoA reductase-related male sterility protein; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. Involved in the synthesis of the lipid component in sporopollenin (616 aa)
     
   
  0.952
ABCG26
ABC-2 type transporter family protein; Encodes a ATP-binding cassette transporter G26 (ABCG26) involved in tapetal cell and pollen development. Required for male fertility and pollen exine formation (685 aa)
     
   
  0.926
TKPR1
Tetraketide alpha-pyrone reductase 1; Involved in the biosynthesis of hydroxylated tetraketide compounds that serve as sporopollenin precursors (the main constituents of exine). Is essential for pollen wall development. Acts on tetraketide alpha-pyrones and reduces the carbonyl function on the tetraketide alkyl chain to a secondary alcohol function (326 aa)
     
 
  0.917
MS1
RING/FYVE/PHD zinc finger superfamily protein; Transcriptional activator required for anther and post- meiotic pollen development and maturation. Seems to regulate inflorescence branching and floral development. May control tapetal development by directly regulating tapetal programmed cell death (PCD) and breakdown. Implicated in pollen cytosolic components and wall development (e.g. exine and intine formation) (672 aa)
     
   
  0.905
TKPR2
NAD(P)-binding Rossmann-fold superfamily protein; May be involved in the biosynthesis of hydroxylated tetraketide compounds that serve as sporopollenin precursors (the main constituents of exine). Acts on tetraketide alpha-pyrones and reduces the carbonyl function on the tetraketide alkyl chain to a secondary alcohol function; Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily (321 aa)
       
 
  0.843
LTP12
Non-specific lipid-transfer protein 12; Encodes a member of the lipid transfer protein family. Proteins of this family are generally small (~9 kD), basic, expressed abundantly and contain eight Cys residues. The proteins can bind fatty acids and acylCoA esters and can transfer several different phospholipids. They are localized to the cell wall. The LTP12 promoter is active exclusively in the tapetum during the uninucleate microspore and bicellular pollen stages. Predicted to be a member of PR-14 pathogenesis-related protein family with the following members- At2g38540/LTP1, At2g [...] (119 aa)
     
   
  0.822
AMS
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Transcription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther. Binds E-box regions in the AHL16/TEK promoter (571 aa)
     
   
  0.820
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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