STRINGSTRING
PRD3 protein (Arabidopsis thaliana) - STRING interaction network
"PRD3" - Putative recombination initiation defects 3 in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRD3Putative recombination initiation defects 3 (449 aa)    
Predicted Functional Partners:
PRD1
Protein PRD1; Required for meiotic double-strand break formation (1268 aa)
     
   
  0.834
MPS1
MULTIPOLAR SPINDLE 1 (385 aa)
           
  0.807
Hop1
Hop1; Mediates the association of the molecular chaperones HSP70 and HSP90. Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity) (572 aa)
     
   
  0.754
HOP2
Arabidopsis Hop2 homolog; Involved in bivalent formation and segregation of homologous chromosomes in meiosis (226 aa)
     
   
  0.747
TAF11
TBP-associated factor 11; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription (210 aa)
           
  0.739
ASY1
ASYNAPTIC 1 (596 aa)
           
  0.732
DFO
DSB formation (233 aa)
           
  0.709
SDS
cyclin-SDS; Meiosis-specific cyclin. Required for normal homolog synapsis and recombination in early to mid-prophase 1. May regulate the timing of sister chromatid separation (578 aa)
     
   
  0.676
FANCM
Fanconi anemia group M protein (1390 aa)
     
   
  0.661
ATSPO11-1
Meiotic recombination protein SPO11-1; Component of a topoisomerase 6 complex specifically required for meiotic recombination (PubMed-11157765, PubMed-17018031, PubMed-17965269, PubMed-26917763). Together with MTOPVIB, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (PubMed-26917763). The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles (PubMed-11157765, PubMed-17018031, PubMed-17965269, PubMed-26917763) (362 aa)
     
   
  0.648
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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