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SPL8 protein (Arabidopsis thaliana) - STRING interaction network
"SPL8" - Squamosa promoter-binding-like protein 8 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
SPL8Squamosa promoter-binding-like protein 8; Trans-acting factor that binds specifically to the consensus nucleotide sequence 5’-TNCGTACAA-3’. Binds specifically to the 5’-GTAC-3’ core sequence. Involved in development and floral organogenesis. Required for ovule differentiation, pollen production, filament elongation, seed formation and siliques elongation. Also seems to play a role in the formation of trichomes on sepals. May positively modulate gibberellin (GA) signaling in flower (333 aa)    
Predicted Functional Partners:
Agamous-like MADS-box protein AGL18; Probable transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Prevents premature flowering. Downstream regulator of a subset of the MIKC* MADS-controlled genes required during pollen maturation (256 aa)
K-box region and MADS-box transcription factor family protein; Transcription factor that promotes early floral meristem identity in synergy with LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Is indispensable for normal development of sepals and petals in flowers. Regulates positively the B class homeotic proteins APETALA3 and PISTILLATA with the cooperation of LEAFY and UFO. Interacts with SEPALLATA3 or AP3/PI heterodimer to form complexes that could be involved in genes regulation during floral meristem development. Regulates p [...] (256 aa)
Subtilisin-like protease SBT3.1; Subtilase family protein; Its function is described as identical protein binding, serine-type endopeptidase activity; Involved in proteolysis, pollen tube growth; Located in endomembrane system; Expressed in pollen tube; Expressed during M germinated pollen stage; Contains the following InterPro domains- Peptidase S8/S53, subtilisin/kexin/sedolisin (InterPro-IPR000209), Proteinase inhibitor I9, subtilisin propeptide (InterPro-IPR010259), Peptidase S8/S53, subtilisin, active site (InterPro-IPR022398), Peptidase S8, subtilisin-related (InterPro-IPR015500) [...] (803 aa)
K-box region and MADS-box transcription factor family protein; Probable transcription factor involved in the control of organ identity during the early development of flowers. Is required for normal development of stamens and carpels in the wild-type flower. Plays a role in maintaining the determinacy of the floral meristem. Acts as C class cadastral protein by repressing the A class floral homeotic genes like APETALA1. Forms a heterodimer via the K-box domain with either SEPALATTA1/AGL2, SEPALATTA2/AGL4, SEPALLATA3/AGL9 or AGL6 that could be involved in genes regulation during floral [...] (252 aa)
Putative MYB family transcription factor; Member of MYB3R- and R2R3- type MYB- encoding genes (370 aa)
Basic blue protein; Forms a concentration gradient along the pollen tube growth path, with a lower level in the stigma papilla cell wall and a higher level in the transmitting tract extracellular matix of the style (129 aa)
PATELLIN 1; Carrier protein that may be involved in membrane- trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds to phosphoinositides with a preference for PtdIns(5)P, PtdIns(4,5)P2 and PtdIns(3)P; Belongs to the patellin family (573 aa)
Transcription factor MYB80; Transcription factor that binds to the DNA sequence 5’- CCAACC-3’. Regulates directly PME5, UND and GLOX1. Essential for tapetum development in anthers and microsporogenesis. Regulates the timing of tapetal programmed cell death (PCD) which is critical for pollen development. May act through the activation of UND, encoding an A1 aspartic protease. Required for anther development by regulating tapetum development, callose dissolution and exine formation. Acts upstream of A6 and FAR2/MS2, two genes required for pollen exine formation. Negatively regulates tric [...] (320 aa)
Detoxifying efflux carrier 35; Encodes a multidrug and toxin efflux family transporter. Involved in flavonoid metabolism, affecting Root growth, seed development and germination, and pollen development, release and viability (514 aa)
MADS-box protein AGL42; MADS-box transcription factor that acts with AGL71 and AGL72 in the control of flowering time. Promotes flowering at the shoot apical and axillary meristems. Seems to act through a gibberellin-dependent pathway. Interacts genetically with SOC1 and its expression is directly regulated by SOC1. Plays a role in controlling flower organ senescence and abscission by repressing ethylene responses and regulating the expression of BOP2 and IDA (210 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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