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VAD1 protein (Arabidopsis thaliana) - STRING interaction network
"VAD1" - Encodes VAD1 (Vascular Associated Death1), a regulator of cell death and defense responses in vascular tissues. VAD1 is a putative membrane associated protein and contains a GRAM domain. vad1 is a lesion mimic mutant that exhibits light conditional appearance of propagative HR (hypersensitive response)-like lesions along the vascular system in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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VAD1Encodes VAD1 (Vascular Associated Death1), a regulator of cell death and defense responses in vascular tissues. VAD1 is a putative membrane associated protein and contains a GRAM domain. vad1 is a lesion mimic mutant that exhibits light conditional appearance of propagative HR (hypersensitive response)-like lesions along the vascular system (598 aa)    
Predicted Functional Partners:
AT5G18370
Disease resistance protein (TIR-NBS-LRR class) family; TIR-NB-LRR receptor-like protein involved in plant defense. Acts as a trigger of hypersensitive response (HR). Functions as guard of CAMTA3, a negative regulator of immunity, during pathogen infection (1210 aa)
           
  0.775
LAC2
Laccase-2; Lignin degradation and detoxification of lignin-derived products (By similarity). Required for root elongation in dehydration conditions; Belongs to the multicopper oxidase family (573 aa)
           
  0.734
EDS1
alpha/beta-Hydrolases superfamily protein; Positive regulator of basal resistance and of effector- triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins. Disruption by bacterial effector of EDS1-TIR- NB-LRR resistance protein interactions constitutes the first step in resistance activation. Acts redundantly with salicylic acid to regulate resistance gene-mediated signaling. Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of salicylic acid. Nuclear loc [...] (623 aa)
           
  0.708
At1g28200
VirF-interacting protein FIP1 (259 aa)
           
  0.641
PLA2A
Patatin-like protein 2; Possesses non-specific lipolytic acyl hydrolase (LAH) activity. Catalyzes the hydrolysis of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), and less efficiently the phoshpolipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidic acid (PA), phosphatidylserine (PS) and phosphatidylinositol (PI). Favors the release of fatty acid at the sn-1 position for PC or PE and the sn-2 position for PG, PA, PS and PI. Negatively affects disease resistance to the necrotic fungal pathogen [...] (407 aa)
           
  0.628
AT3G48080
alpha/beta-Hydrolases superfamily protein; Acts as a second functional copy of EDS1. Can mediate HRT-mediated resistance to turnip crinkle virus (629 aa)
     
   
  0.577
AT1G33270
Acyl transferase/acyl hydrolase/lysophospholipase superfamily protein; Lipolytic acyl hydrolase (LAH) (369 aa)
           
  0.575
APG9
Autophagy-related protein 9; Required for autophagy that plays an essential role in plant nutrient recycling. Contributes to efficient autophagic flux, especially in early autophagic process prior to the fusion of the autophagosome with the vacuole; Belongs to the ATG9 family (866 aa)
     
   
  0.570
AtLEA4-1
Late embryogenesis abundant protein, group 1 protein; Involved dehydration tolerance. Involved in the adaptive response of vascular plants to withstand water deficit. May possess chaperone-like activity under water deficit (By similarity) (134 aa)
           
  0.569
MTM2
Phosphatidylinositol-3-phosphatase myotubularin-2; Phosphatase with phosphoinositide 3’-phosphatase activity that can use phosphatidylinositol-3-phosphate (PtdIns3P) and phosphatidylinositol-3,5-diphosphate (PtdIns3,5P(2)) as substrates and produces phosphatidylinositol-5-phosphate (PtdIns5P); participates in pathway(s) that transfer gene regulatory signals to the nucleus; Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily (833 aa)
     
   
  0.566
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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