Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
NAC domain containing protein 5 (362 aa)
Predicted Functional Partners:
Member of CYP96A (506 aa)
Myb family transcription factor (432 aa)
Restricted tev movement 1; Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance (174 aa)
Myb family transcription factor (235 aa)
CLAVATA3/ESR-RELATED 6; Extracellular signal peptide that regulates cell fate (81 aa)
Expansin A9; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity) (258 aa)
Myb family transcription factor (394 aa)
Zinc finger WD40 repeat protein 1 (430 aa)
Ubiquitin-conjugating enzyme 30; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (148 aa)
SRPBCC ligand-binding domain-containing protein (152 aa)
Your Current Organism:
NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress