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TPK4 protein (Arabidopsis thaliana) - STRING interaction network
"TPK4" - Outward rectifying potassium channel protein in Arabidopsis thaliana
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Predicted Interactions
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TPK4Outward rectifying potassium channel protein; Voltage-independent, instantaneously activating, potassium-selective plasma membrane ion channel. Open rectifier. Regulated by cytoplasmic pH and extra-cellular calcium. Has some permeability for Rb(+) and NH(4)(+), but none for Na(+) or Li(+) (284 aa)    
Predicted Functional Partners:
SPIK
Shaker pollen inward K+ channel; Highly selective inward-rectifying potassium channel that could mediate potassium uptake in the pollen membrane. Plays an important role in pollen tube development. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization. May interact with the cytoskeleton or with regulatory proteins (888 aa)
       
 
  0.829
SKOR
Potassium channel SKOR; Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins (828 aa)
       
 
  0.768
KT5
K+ transporter 5; Probable potassium channel. May interact with the cytoskeleton or with regulatory proteins (By similarity) (880 aa)
       
 
  0.717
KT2/3
Potassium transport 2/3; Highly selective and weak inward-rectifying potassium channel. Plays a role in both loading and unloading potassium into/from the phloem sap. Seems to control sugar loading into phloem via a voltage-dependent process. Blocked by physiological concentrations of external calcium and by external acidification. May interact with the cytoskeleton or with regulatory proteins. Dephosphorylation by PP2CA not only leads to the inhibition of potassium currents but also to an increase of the voltage- dependence of the channel. Regulated by the CBL4/CIPK6 calcium sensor/pr [...] (802 aa)
       
 
  0.717
GORK
Potassium channel GORK; Major selective outward-rectifying potassium channel of the guard cell membrane. Involved in regulation of stomatal movements according to the water status. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. Conductance of the channel is modulated in a potassium-dependent fashion. May interact with the cytoskeleton or with regulatory proteins (820 aa)
       
 
  0.710
SETH3
Sugar isomerase (SIS) family protein; Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (350 aa)
         
  0.689
AKT1
K+ transporter 1; Highly selective inward-rectifying potassium channel that mediate potassium uptake by plant roots in response to low K(+) conditions, by a calcium-, CBL-, and CIPK-dependent pathway. Positively regulated by phosphorylation by CIPK23. Negatively regulated by a kinase-independent regulatory mechanism involving a competing direct binding of CBL10. Involved in the stomatal regulation by monitoring the turgor pressure in guard cells. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarizat [...] (857 aa)
       
 
  0.681
CBL1
Calcineurin B-like protein 1; Acts as a calcium sensor involved in the signaling pathway during growth and development and in response to abiotic stresses. May function as a positive regulator of salt and drought responses and as a negative regulator of cold response. Contributes to the regulation of early stress-related CBF/DREB transcription factors. CBL proteins interact with CIPK serine- threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT [...] (213 aa)
       
 
  0.670
KEA5
K+ efflux antiporter 5; K(+)/H(+) antiporter involved in K(+) homeostasis and osmotic adjustment (568 aa)
         
  0.651
SOS3
SALT OVERLY SENSITIVE 3; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the endoplas [...] (222 aa)
       
 
  0.633
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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