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ABCB11 protein (Arabidopsis thaliana) - STRING interaction network
"ABCB11" - ABC transporter B family member 11 in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
ABCB11ABC transporter B family member 11; P-glycoprotein 11 (PGP11); Its function is described as ATPase activity, coupled to transmembrane movement of substances; Involved in transport, transmembrane transport; Located in plasma membrane; Expressed in callus; Contains the following InterPro domains- ATPase, AAA+ type, core (InterPro-IPR003593), ABC transporter-like (InterPro-IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro-IPR011527), ABC transporter integral membrane type 1 (InterPro-IPR017940), ABC transporter, transmembrane domain (InterPro-IPR001140), ABC transporter, [...] (1278 aa)    
Predicted Functional Partners:
GSTT3
Glutathione S-transferase THETA 3; May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides (590 aa)
       
 
  0.833
PAPP2C
Encodes a phytochrome-associated protein, PAPP2C (phytochrome-associated protein phosphatase type 2C). PAPP2C interacts in the nucleus with phyA (phytochrome A) and phyB. Functions as a regulator of phytochrome-interacting factor PIF3 by dephosphorylating phytochromes in the nucleus (287 aa)
           
  0.710
ABCA11
Member of ATH subfamily (919 aa)
     
 
  0.690
THY-2
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (565 aa)
   
   
  0.579
AT2G21550
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (492 aa)
   
   
  0.579
THY-1
Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (519 aa)
   
   
  0.579
ABCG29
ABC transporter G family member 29; May be a general defense protein (1416 aa)
     
 
  0.540
PPI1
Proton pump-interactor 1; Promotes AHA1 plasma membrane ATPase activity by binding to a site different from the 14-3-3 binding site (612 aa)
     
   
  0.537
ABCE3
Member of NAP subfamily (181 aa)
           
  0.516
PGP1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1, chloroplastic; Catalyzes the committed step to the synthesis of the acidic phospholipids. Transfers specifically a phosphatidyl group from CDP-diacylglycerol to glycerol-3-phosphate to form phosphatidylglycerophosphate. Cannot catalyze the phosphatidyl group transfer to inositol, serine, choline or phosphatidylglycerol. Possesses high activity with CDP- dipalmitoylglycerol and low activity with CDP-dioleoylglycerol (296 aa)
         
  0.509
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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