• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
IMPA-6 protein (Arabidopsis thaliana) - STRING interaction network
"IMPA-6" - Importin subunit alpha-6 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IMPA-6Importin subunit alpha-6; Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation; Belongs to the importin alpha family (539 aa)    
Predicted Functional Partners:
AT2G46520
Cellular apoptosis susceptibility protein, putative / importin-alpha re-exporter, putative; Export receptor for importin alpha. Mediates importin- alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity) (972 aa)
     
 
  0.903
AT3G08943
ARM repeat superfamily protein; Its function is described as protein transporter activity, binding; Involved in intracellular protein transport; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Importin-beta, N-terminal (InterPro-IPR001494), Armadillo-like helical (InterPro-IPR011989), Armadillo-type fold (InterPro-IPR016024); BEST Arabidopsis thaliana protein match is- ARM repeat superfamily protein (TAIR-AT3G08947.1); Has 1770 Blast hits to 1697 proteins in 220 species- Archae - 0; Bacteria - 0; Metazoa - 669; Fungi - 578; Plants - 273; Viruses - 0; Other Eukaryote [...] (871 aa)
     
 
  0.846
AT3G08947
ARM repeat superfamily protein; Its function is described as protein transporter activity, binding; Involved in intracellular protein transport; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Importin-beta, N-terminal (InterPro-IPR001494), Armadillo-like helical (InterPro-IPR011989), Armadillo-type fold (InterPro-IPR016024); BEST Arabidopsis thaliana protein match is- ARM repeat superfamily protein (TAIR-AT3G08943.1); Has 1718 Blast hits to 1652 proteins in 220 species- Archae - 0; Bacteria - 1; Metazoa - 645; Fungi - 556; Plants - 267; Viruses - 0; Other Eukaryote [...] (873 aa)
     
 
  0.836
AT5G53480
ARM repeat superfamily protein; Acts as negative effector of drought tolerance. Involved in the regulation of stomatal closure and in the abscisic acid (ABA)-mediated pathway that lead to drought tolerance. Does not directly mediate nuclear import of ABI1 and ABI2 which are key regulators of the ABA signaling pathway. May be involved in nuclear translocation of other type 2C protein phosphatases that mediate ABA signaling (870 aa)
     
 
  0.833
AtCg00800
Encodes a chloroplast ribosomal protein S3, a constituent of the small subunit of the ribosomal complex; Belongs to the universal ribosomal protein uS3 family (218 aa)
     
 
  0.832
SDH1-2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (632 aa)
     
 
  0.787
CBP20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with t [...] (257 aa)
     
 
  0.786
AT5G35910
Polynucleotidyl transferase, ribonuclease H fold protein with HRDC domain; Acts as an important epigenetic regulator through multiple silencing mechanisms. Involved in association with RRP6L1 in the silencing of the solo LTR locus. Controls levels of non-coding RNAs (ncRNAs) from the solo LTR locus. Seems to function independently of the RNA- mediated gene silencing (RdDM) pathway. Functions redundantly with RRP6L1 in the regulation of FLC locus. Participates in the maintenance of trimethylated ’Lys-27’ (H3K27me3) at FLC locus via the regulation of antisense long non- coding RNAs (lncR [...] (870 aa)
     
 
  0.779
ABH1
Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state [...] (848 aa)
     
 
  0.776
APM1
Aminopeptidase M1; Metallopeptidase that binds to the auxin transport inhibitor N-1-naphthylphthalamic acid (NPA). Required for embryonic and seedling development as well as cell cycle progression. Homodimerization is required to proper localization and activity. May play a negative role in the regulation of PIN auxin transport proteins (879 aa)
     
   
  0.769
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]