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D27 protein (Arabidopsis thaliana) - STRING interaction network
"D27" - DWARF27 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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textmining
co-expression
protein homology
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D27DWARF27; Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta- carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds (264 aa)    
Predicted Functional Partners:
CCD7
Carotenoid cleavage dioxygenase 7; Involved in strigolactones biosynthesis by cleaving asymmetrically a variety of linear and cyclic carotenoids at the 9-10 double bond. Produces one C(13) beta-ionone and the C(27) 10’-apo-beta-carotenal. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds. [...] (629 aa)
         
  0.986
CHY2
Beta-carotene hydroxylase 2; Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylations of beta-carotene. Has also a low activity toward the beta- and epsilon-rings of alpha-carotene. No activity with acyclic carotenoids such as lycopene and neurosporene. Uses ferredoxin as an electron donor (Probable) (303 aa)
     
 
    0.909
At4g25700
Beta-hydroxylase 1; Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylations of beta-carotene. Has also a low activity toward the beta- and epsilon-rings of alpha-carotene. No activity with acyclic carotenoids such as lycopene and neurosporene. Uses ferredoxin as an electron donor (Probable) (310 aa)
         
    0.900
LYC
Lycopene cyclase; Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene (501 aa)
         
    0.900
CYP97A3
Cytochrome P450, family 97, subfamily A, polypeptide 3; Heme-containing cytochrome P450 involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylation of alpha- and beta-carotene. Has also a low activity toward the epsilon-rings of alpha-carotene. The beta-ring of alpha-carotene is the preferred substrate in planta (595 aa)
         
    0.900
CCD8
Carotenoid cleavage dioxygenase 8; Involved in strigolactones biosynthesis by cleaving the C(27) 9-cis-10’-apo-beta-carotenal produced by CCD7. Produces the C(19) carlactone and a C(8) hydroxyaldehyde. Also shows lower activity with all-trans-10’-apo-beta-carotenal producing a C(9) dialdehyde and the C(18) 13-apo-beta-carotenone. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal br [...] (570 aa)
     
   
  0.884
CYP711A1
Cytochrome P450, family 711, subfamily A, polypeptide 1; Converts carlactone to carlactonoic acid by catalyzing consecutive oxidations at C-19 to convert the C-19 methyl group into carboxylic acid (PubMed-25425668). Prefers 11R-carlactone to 11S-carlactone as substrate (PubMed-25425668). Acts downstream of CCD7/MAX3 and CCD8/MAX4 in strigolactone signaling pathway and may be implicated in synthesis of carotenoid-derived branch regulators. Acts as a positive regulator of the flavonoid pathway in the late vegetative stage plant. Strigolactones are hormones that inhibit tillering and shoo [...] (522 aa)
           
  0.869
AT3G03990
alpha/beta-Hydrolases superfamily protein; Involved in strigolactone signaling pathway (PubMed-22357928). Does not move long distances acropetally in the plant to regulate shoot branching and is rapidly degraded in the presence of strigolactones (PubMed-24610723). May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form (PubMed-22357928). Acts probably as a strigolactone receptor (PubMed-24610723). Strigolactones are hormones that inhibit tillering and shoot branch [...] (267 aa)
           
  0.863
MAX2
F-box protein ORE9; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the senescence. Is necessary for responses to strigolactones and karrikins. Contributes to the selective repression of axillary shoots and moderates the branching by regulating negatively the auxin transport in primary stems, in an AXR1-independent manner (PubMed-11487692, PubMed-11874909, PubMed-15737939, PubMed-16546078, PubMed-22357928, PubMed-9351240). Required for the progression of leaf senes [...] (693 aa)
           
  0.840
RL5
RAD-like 5; Probable transcription factor (100 aa)
           
  0.741
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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