• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
SPI protein (Arabidopsis thaliana) - STRING interaction network
"SPI" - Beige/BEACH domain in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIBeige/BEACH domain ;WD domain, G-beta repeat protein; Involved in cell morphogenesis. May have a function in membrane fusion or membrane composition. Required for salt stress tolerance. Regulates the salt stress-dependent post- transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress-regulated mRNAs (3601 aa)    
Predicted Functional Partners:
PEUP1
Autophagy-related protein 2; Required for autophagy that plays an essential role in plant nutrient recycling. Involved in the early steps of autophagosome biogenesis. Involved in the negative regulation of plant defense responses to biotrophic pathogens. Involved in a negative feedback loop that modulates NPR1-dependent salicylic acid (SA) signaling and limits senescence and immunity-related programmed cell death (PCD) in plants. Involved in the degradation of damaged peroxisomes (1839 aa)
     
 
  0.966
APG5
Autophagy protein Apg5 family; Required for autophagy. Conjugation to ATG12 is essential for plant nutrient recycling. Involved in a negative feedback loop that modulates NPR1-dependent salicylic acid (SA) signaling and limits senescence and immunity- related programmed cell death (PCD) in plants. Involved in complete proteolysis of chloroplast stroma proteins in senescent leaves. Involved in the degradation of damaged peroxisomes; Belongs to the ATG5 family (337 aa)
       
 
  0.964
FANCM
DEAD-box ATP-dependent RNA helicase FANCM; Involved in ordered homologous recombination (HR) events in somatic and meiotic cells. Involved in the suppression of spontaneous HR events in somatic cells. Has an opposite function to the DNA binding cofactor MHF1 which promotes spontaneous HR. Functions in replicative repair independently of MHF1 and in a parallel pathway to the endonuclease MUS81. Acts in the same pathway as the two DNA-binding cofactors MHF1 and MHF2 to restrain class II meiotic crossover (CO), and acts exclusively with MHF1 and MHF2 during meiosis to repair DNA interstra [...] (1390 aa)
     
   
  0.943
APG8A
Ubiquitin-like superfamily protein; Encodes APG8, a component of autophagy conjugation pathway. Delivered to the lumens of vacuole under nitrogen-starvation condition. Highest expression in flowers. mRNA abundance increased during dark-induced carbon starvation. Predominantly cytoplasmic with or without N starvation. Upon concanamycin A the protein accumulates in the central vacuole as punctuate structures that resemble autophagic bodies. This localization is more abundant upon N starvation (137 aa)
       
 
  0.943
ATG8F
Ubiquitin-like superfamily protein; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (121 aa)
       
 
  0.943
ATG8B
Ubiquitin-like superfamily protein; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (122 aa)
       
 
  0.943
ATG8G
Ubiquitin-like superfamily protein; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (121 aa)
       
 
  0.943
APG8H
Ubiquitin-like superfamily protein; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (115 aa)
       
 
  0.943
ATG8H
Ubiquitin-like superfamily protein; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton; Belongs to the ATG8 family (119 aa)
       
 
  0.943
ATG8E
Autophagy-related protein 8e; Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (122 aa)
       
 
  0.943
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]