STRINGSTRING
UVH6 protein (Arabidopsis thaliana) - STRING interaction network
"UVH6" - DNA repair helicase UVH6 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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UVH6DNA repair helicase UVH6; Putative ATP-dependent 5’-3’ DNA helicase involved in nucleotide excision repair (NER) of UV-damaged DNA. May open DNA around the damage. Essential during plant growth. May negatively regulate a common response program mediated by UV damage and heat stress, that leads to tissue death and reduced chloroplast function (758 aa)    
Predicted Functional Partners:
AT4G17020
Transcription factor-related; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (482 aa)
     
  0.999
AT4G30820
CDK-activating kinase assembly factor MAT1 (178 aa)
     
  0.999
CYCH;1
Cyclin H;1; Associates with CDK-2 and CDK-3 and activates the CDK kinases (336 aa)
     
  0.999
AT1G55750
Transcription initiation factor TFIIH subunit H1; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (591 aa)
     
  0.999
CAK4
CDK-activating kinase 4; Forms a stable complex with cyclin CYCH1-1 that phosphorylates human CDK2 and the C-terminal domain (CTD) of the large subunit of RNA polymerase II (348 aa)
     
  0.999
GTF2H2
General transcription factor II H2; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. Can restore UV resistance in the NER-deficient ssl1-1 yeast mutant (421 aa)
     
  0.999
XPB2
DNA repair helicase XPB2; Putative ATP-dependent 3’-5’ DNA helicase involved in nucleotide excision repair (NER) of DNA. May be involved in RNA transcription by RNA polymerase II. Acts by opening DNA around either the RNA transcription start site or the DNA damage (766 aa)
     
  0.999
XPB1
DNA repair helicase XPB1; Putative ATP-dependent 3’-5’ DNA helicase involved in nucleotide excision repair (NER) of DNA. May be involved in RNA transcription by RNA polymerase II. Acts by opening DNA around either the RNA transcription start site or the DNA damage (By similarity). Required during the early stages of development, including seed germination (PubMed-11737776) (767 aa)
     
  0.999
AT4G30825
Pentatricopeptide repeat-containing protein (904 aa)
     
 
  0.999
AT1G18340
Transcription initiation factor TFIIH subunit H3; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (301 aa)
     
  0.998
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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