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RRP4 protein (Arabidopsis thaliana) - STRING interaction network
"RRP4" - Exosome complex component RRP4 homolog in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RRP4Exosome complex component RRP4 homolog; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is an active and distributive 3’->5’ exonuclease requiring a free 3’-OH on the substrate and releasing nucleoside 5’-monophosphates. Required for normal embryo development; Belongs to the RRP4 family (322 aa)    
Predicted Functional Partners:
AT3G46210
Ribosomal protein S5 domain 2-like superfamily protein; Probable component of the exosome 3’->5’ exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3’-untranslated regions (239 aa)
   
  0.999
RRP41
Exosome complex component RRP41 homolog; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is a processive phosphorolytic exonuclease and requires a single-stranded poly(A) tail on the substrate RNA for its activity. Can complement the growth defect of a yeast mutant lacking RRP41 exonuclease. Required for normal development of female gametophytes (241 aa)
   
  0.999
AT3G07750
3’-5’-exoribonuclease family protein; Its function is described as 3’-5’-exoribonuclease activity, RNA binding; Involved in RNA processing; Located in cellular_component unknown; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Exoribonuclease, phosphorolytic domain 2 (InterPro-IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro-IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro-IPR020568); BEST Arabidopsis thaliana protein match is- ribonuclease PH45A (TAIR-AT3G12990.3); Has 1493 Blast hits to 1491 prot [...] (286 aa)
   
  0.999
AT1G60080
3’-5’-exoribonuclease family protein; Its function is described as 3’-5’-exoribonuclease activity, RNA binding; Involved in RNA processing; Located in cellular_component unknown; Expressed in 20 plant structures; Expressed during 12 growth stages; Contains the following InterPro domains- Exoribonuclease, phosphorolytic domain 2 (InterPro-IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro-IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro-IPR020568); BEST Arabidopsis thaliana protein match is- ribonuclease PH45A (TAIR-AT3G12990.3); Has 1508 Blast hits to 1508 prot [...] (302 aa)
 
  0.999
CER7
3’-5’-exoribonuclease family protein; Probable 3’->5’ exoribonuclease involved in the regulation of cuticular wax biosynthesis by controlling the expression of CER3. May act by degrading a specific mRNA species encoding a negative regulator of CER3 transcription. Can perform exosomal functions and complement the yeast rrp45 null mutant (438 aa)
   
  0.999
AT2G25355
PNAS-3-like protein; PNAS-3 related; Involved in N-terminal protein myristoylation; Located in cellular_component unknown; Expressed in 14 plant structures; Expressed during 6 growth stages; BEST Arabidopsis thaliana protein match is- PNAS-3 related (TAIR-AT4G32175.1); Has 410 Blast hits to 410 proteins in 205 species- Archae - 27; Bacteria - 0; Metazoa - 113; Fungi - 136; Plants - 59; Viruses - 0; Other Eukaryotes - 75 (source- NCBI BLink) (241 aa)
     
  0.999
RRP41L
3’-5’-exoribonuclease family protein; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is a processive phosphorolytic exonuclease and requires a single-stranded poly(A) tail on the substrate RNA for its activity (By similarity). Plays an important role in seed germination and early seedling growth by mediating specific cytoplasmic mRNA decay of transcripts coding for the abscisic acid (ABA) biosynthetic enzymes NCED5 and NCED6, and the ABA [...] (256 aa)
   
  0.999
AT5G38890
Nucleic acid-binding, OB-fold-like protein; Its function is described as RNA binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Ribosomal protein S1, RNA-binding domain (InterPro-IPR003029), Exosome complex, component CSL4 (InterPro-IPR019495); Has 35333 Blast hits to 34131 proteins in 2444 species- Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source- NCBI BLink) (191 aa)
     
  0.999
MTR4
RNA helicase, ATP-dependent, SK12/DOB1 protein; ATP-dependent RNA helicase that associates with the RNA exosome complex. Required for proper rRNA biogenesis and development. Involved in the 3’- processing of the 7S pre-RNA to the mature 5.8S rRNA and also in the removal of rRNA maturation by-products (988 aa)
     
  0.999
RRP45a
Exosome complex component RRP45A; Probable 3’->5’ exoribonuclease involved in the regulation of cuticular wax biosynthesis. Can perform exosomal functions and partially complement the yeast rrp45 null mutant; Belongs to the RNase PH family (307 aa)
   
  0.999
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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