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BSU1 protein (Arabidopsis thaliana) - STRING interaction network
"BSU1" - BRI1 SUPPRESSOR 1 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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BSU1BRI1 SUPPRESSOR 1; Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling (PubMed-14977918, PubMed-21855796). Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs (PubMed-14977918). Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at ’Tyr-200’ (PubMed-21855796) (793 aa)    
Predicted Functional Partners:
BSK1
BR-signaling kinase 1 (512 aa)
         
  0.988
BIN2
BRASSINOSTEROID-INSENSITIVE 2; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5 (380 aa)
       
 
  0.974
CDG1
Protein kinase family protein; Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth. Mediates BR signal transduction from BRI1 receptor kinase to BSU1 phosphatase. After activation by phosphorylation at Ser-234 by BRI1, CDG1 phosphorylates BSU1 at ’Ser-764’ in the phosphatase domain, increasing the ability of BSU1 to inactivate the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at ’Tyr- 200’. The full kinase activity of CDG1 is required for its biological function (432 aa)
       
 
  0.956
BSK3
BR-signaling kinase 3 (489 aa)
       
  0.955
BES1
BRI1-EMS-SUPPRESSOR 1; Positive brassinosteroid-signaling protein. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5’-CANNTG-3’(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (357 aa)
           
  0.955
BZR1
BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5’-CGTG(T/C)G-3’ in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2) (336 aa)
     
   
  0.928
BKI1
BRI1 kinase inhibitor 1; Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1 (337 aa)
           
  0.920
NRPD1B
Nuclear RNA polymerase D1B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements. Also required for full erasure of methylation when the RNA trigger is withdrawn. Seems also involved in the synthesis of short-interfering RNAs (siRNA). Essential component of a self- reinforcing loop coupling de novo DNA methylation to siRNA pr [...] (1976 aa)
       
 
  0.910
BSK4
Brassinosteroid-signaling kinase 4 (483 aa)
         
  0.884
BRI1
BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphoryla [...] (1196 aa)
           
  0.868
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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