STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAMP4Secretory carrier membrane protein (SCAMP) family protein; Probably involved in membrane trafficking (283 aa)    
Predicted Functional Partners:
PLDP2
Phospholipase D zeta 2; Encodes a member of the PXPH-PLD subfamily of phospholipase D proteins. Regulates vesicle trafficking. Required for auxin transport and distribution and hence auxin responses. This subfamily is novel structurally different from the majority of plant PLDs by having phox homology (PX) and pleckstrin homology (PH) domains. Involved regulating root development in response to nutrient limitation. Plays a major role in phosphatidic acid production during phosphate deprivation. Induced upon Pi starvation in both shoots and roots. Involved in hydrolyzing phosphatidyl [...]
     
 0.906
AT3G27870
ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein; Involved in transport of phospholipids
   
  0.905
AT1G69450
Early-responsive to dehydration stress protein (ERD4); Acts as an osmosensitive calcium-permeable cation channel
   
 0.903
SCAMP2
Secretory carrier membrane protein (SCAMP) family protein; Probably involved in membrane trafficking
     
0.902
SCAMP5
Secretory carrier-associated membrane protein 4; Probably involved in membrane trafficking
     
0.902
SC3
Encodes a putative secretory carrier membrane protein (SC3)
     
0.902
AT1G10730
Clathrin adaptor complexes medium subunit family protein; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE). The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Functions redundantly with AP1M2 in multiple post-Golgi trafficking pathways leading from the TGN to the vacuole, the plasma membrane, and the cell-division plane
   
 
  0.901
ACA.l
Probable phospholipid-transporting ATPase 11; Involved in transport of phospholipids
   
  0.901
AT1G17500
ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein; Involved in transport of phospholipids
   
  0.901
AT1G26130
ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein; Involved in transport of phospholipids; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily
   
  0.901
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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