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RING1B protein (Arabidopsis thaliana) - STRING interaction network
"RING1B" - Putative E3 ubiquitin-protein ligase RING1b in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RING1BPutative E3 ubiquitin-protein ligase RING1b; Encodes a nuclear localized protein with similarity to animal polycomb repressive core complex1 (PRC1) core component RING.Appears to function redundantly with ATRING1a, a close paralog. Both interact physically with CLF and LHP1 and appear to function together to repress class I KNOX gene expression (468 aa)    
Predicted Functional Partners:
DRIP2
E3 ubiquitin protein ligase DRIP2; E3 ubiquitin-protein ligase that acts as a negative regulator of the response to water stress. Mediates ubiquitination and subsequent proteasomal degradation of the drought-induced transcriptional activator DREB2A. Functionally redundant with DRIP1 (420 aa)
       
 
  0.969
AT3G23060
Probable E3 ubiquitin protein ligase DRIPH; RING/U-box superfamily protein; Its function is described as zinc ion binding; Expressed in central cell, flower; Expressed during 4 anthesis; Contains the following InterPro domains- Zinc finger, RING-type, conserved site (InterPro-IPR017907), Zinc finger, RING-type (InterPro-IPR001841), Zinc finger, C3HC4 RING-type (InterPro-IPR018957); BEST Arabidopsis thaliana protein match is- DREB2A-interacting protein 2 (TAIR-AT2G30580.1); Has 1905 Blast hits to 1881 proteins in 164 species- Archae - 0; Bacteria - 4; Metazoa - 1370; Fungi - 69; Plants [...] (480 aa)
       
 
  0.949
CLF
Histone-lysine N-methyltransferase CLF; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates ’Lys-27’ of histone H3, leading to transcriptional repression of the affected target genes. Required to regulate floral development by repressing the AGAMOUS homeotic gene in leaves, influorescence stems and flowers. Regulates the antero-posterior organization of the endosperm, as well as the division and elongation rates of leaf cells. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressiv [...] (902 aa)
       
  0.946
SWN
Histone-lysine N-methyltransferase EZA1; Encodes a polycomb group protein. Forms part of a large protein complex that can include VRN2 (VERNALIZATION 2), VIN3 (VERNALIZATION INSENSITIVE 3) and polycomb group proteins FERTILIZATION INDEPENDENT ENDOSPERM (FIE) and CURLY LEAF (CLF). The complex has a role in establishing FLC (FLOWERING LOCUS C) repression during vernalization. Performs a partially redundant role to MEA in controlling seed initiation by helping to suppress central cell nucleusendosperm proliferation within the FG (856 aa)
       
  0.929
TFL2
Chromo domain-containing protein LHP1; Structural component of heterochromatin involved in gene repression, including several floral homeotic genes and FLT that regulates flowering time. Required for maintenance of vernalization-induced repression of FLC. As part of the PRC1-like complex, recognizes and binds histone H3 tails methylated at ’Lys- 9’ (H3K9me) and ’Lys-27’ (H3K27me), leading to epigenetic repression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling a [...] (445 aa)
     
 
  0.912
HTA4
Encodes HTA4, a histone H2A protein (124 aa)
     
 
  0.906
RING1
Encodes a RING finger domain protein with E3 ligase activity that is localized to the lipid rafts of the plasma membrane. Expression is increased in response to fungal pathogen. May be involved in regulation of programmed cell death by facilitating degredation of regulation of PDC activators; Belongs to the RING-type zinc finger family. ATL subfamily (301 aa)
           
  0.898
FIE
Encodes a protein similar to the transcriptional regular of the animal Polycomb group and is involved in regulation of establishment of anterior-posterior polar axis in the endosperm and repression of flowering during vegetative phase. Mutation leads endosperm to develop in the absence of fertilization and flowers to form in seedlings and non-reproductive organs. Also exhibits maternal effect gametophytic lethal phenotype, which is suppressed by hypomethylation. Forms part of a large protein complex that can include VRN2 (VERNALIZATION 2), VIN3 (VERNALIZATION INSENSITIVE 3) and polyco [...] (369 aa)
     
  0.884
AT5G13250
RING finger protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; BEST Arabidopsis thaliana protein match is- RING finger protein (TAIR-AT1G28080.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source- NCBI BLink) (387 aa)
       
 
  0.864
AT1G28080
RING finger protein; BEST Arabidopsis thaliana protein match is- RING finger protein (TAIR-AT5G13250.1); Has 133 Blast hits to 133 proteins in 13 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 133; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (291 aa)
       
 
  0.864
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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