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ABCC5 protein (Arabidopsis thaliana) - STRING interaction network
"ABCC5" - ATP-binding cassette C5 in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ABCC5ATP-binding cassette C5; Pump for glutathione S-conjugates. Involved in regulation of K(+) and Na(+) cell content. Mediates resistance to NaCl and Li(+), confers sensitivity to sulfonylurea drugs such as glibenclamide (inducer of stomatal opening), and required for stomatal opening regulation by auxin, abscisic acid (ABA) and external Ca(2+). Transports oestradiol-17-(beta-D-glucuronide) (E(2)17G). Involved in the root auxin content regulation that controls the transition from primary root elongation to lateral root formation. Plays a role in ABA-mediated germination inhibition (PubMed [...] (1514 aa)    
Predicted Functional Partners:
SETH3
Sugar isomerase (SIS) family protein; Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (350 aa)
   
 
  0.747
ITPK4
Inositol-tetrakisphosphate 1-kinase 4; Kinase that can phosphorylate the inositol polyphosphate Ins(1,3,4)P3 to form InsP4. Also phosphorylates a racemic mixture of Ins(1,4,6)P3 and Ins(3,4,6)P3 to form InsP4. Does not display inositol 3,4,5,6-tetrakisphosphate 1-kinase activity, but possesses inositol 1,4,5,6-tetrakisphosphate and inositol 1,3,4,5- tetrakisphosphate isomerase activity (PubMed-17698066). Ins(1,3,4,6)P4 is an essential molecule in the hexakisphosphate (InsP6) pathway (By similarity) (488 aa)
     
   
  0.680
ITPK1
Inositol (1,3,4) P3 5/6-kinase 1; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway (PubMed-9126335) (319 aa)
           
  0.679
ABCF1
ATP-binding cassette F1 (595 aa)
     
   
  0.666
ABCG32
ATP-binding cassette G32; May be a general defense protein (By similarity). Required for the formation of the cuticle layer of the cell wall (PubMed-21628525) (1420 aa)
       
 
  0.634
FAB1C
FORMS APLOID AND BINUCLEATE CELLS 1C; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity) (1648 aa)
     
 
  0.633
GLU2
Glutamate synthase 2; May play a role in primary nitrogen assimilation in roots. Could supply a constitutive level of glutamate to maintain a basal level of protein synthesis (1629 aa)
   
   
  0.632
LpxK
Lipid X K; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA). Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential) (395 aa)
         
  0.612
At5g16050
General regulatory factor 5; Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. May be involved in cell cycle regulation by binding to soluble EDE1 and sequestering it in an inactive form during the early stages of mitosis (268 aa)
     
      0.610
MPA24.5
BARELY ANY MERISTEM 1; Necessary for male gametophyte development, as well as ovule specification and function. Involved in cell-cell communication process required during early anther development, and regulating cell division and differentiation to organize cell layers. Required for the development of high-ordered vascular strands within the leaf and a correlated control of leaf shape, size and symmetry. May regulate the CLV1-dependent CLV3-mediated signaling in meristems maintenance (1003 aa)
   
 
  0.606
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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