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MAC3A protein (Arabidopsis thaliana) - STRING interaction network
"MAC3A" - Pre-mRNA-processing factor 19 homolog 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MAC3APre-mRNA-processing factor 19 homolog 1; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity). Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity (523 aa)    
Predicted Functional Partners:
EMB14
Pre-mRNA-processing-splicing factor 8A; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex (By similarity). Required for embryo development (Ref.3). Required for splicing efficiency of COOLAIR introns and usage of the proximal poly(A) site. COOLAIR is a set of long non-coding antisense transcripts produced at the FLOWERING LOCUS C (FLC). COOLAIR initiates just downstream of the major sense transcript poly(A) site and terminates either early or extends into the FLC promoter region. S [...] (2359 aa)
     
  0.999
MOS4
Pre-mRNA-splicing factor SPF27 homolog; Encodes MOS4 (Modifier of snc1, 4), a nuclear protein homologous to human Breast Cancer-Amplified Sequence (BCAS2). MOS4 interacts with AtCDC5 and PRL1. All three proteins are essential for plant innate immunity (253 aa)
     
  0.999
CDC5
Cell division cycle 5-like protein; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage; Belongs to the CEF1 family (844 aa)
     
  0.999
emb1507
U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly (2171 aa)
     
  0.999
MEE5
Ribosomal protein S5/Elongation factor G/III/V family protein; Splicing factor involved in pre-mRNA splicing and component of the spliceosome. Essential for reproduction. In female gametophyte, is necessary for the egg cell and central cell fate determination and hence reproductive success. Involved in a mechanism that prevents accessory cells from adopting gametic cell fate. Is necessary to restrict LIS expression to interfere with egg-cell specification. Probable component of U5 small nuclear ribonucleoprotein (snRNP) that is required for pre-mRNA splicing. Plays an essential role in [...] (987 aa)
     
  0.999
AT5G25230
Ribosomal protein S5/Elongation factor G/III/V family protein; Splicing factor involved in pre-mRNA splicing and component of the spliceosome (973 aa)
     
  0.999
SAP130b
Cleavage and polyadenylation specificity factor (CPSF) A subunit protein; Subunit of the splicing factor SF3B required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity). Required for pollen and ov [...] (1214 aa)
     
  0.998
AT1G20580
Small nuclear ribonucleoprotein family protein; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). May play a major role in the splicing of cellular pre-mRNAs. Required for normal plant development (131 aa)
     
  0.998
F17A22.3
Small nuclear ribonucleoprotein family protein; Contains the following InterPro domains- Like-Sm ribonucleoprotein (LSM) domain (InterPro-IPR001163), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro-IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro-IPR010920); BEST Arabidopsis thaliana protein match is- Small nuclear ribonucleoprotein family protein (TAIR-AT2G47640.4); Has 794 Blast hits to 794 proteins in 230 species- Archae - 2; Bacteria - 0; Metazoa - 330; Fungi - 182; Plants - 143; Viruses - 0; Other Eukaryotes - 137 (source- NCBI BLink) (109 aa)
     
  0.998
SmD3
Small nuclear ribonucleoprotein SmD3a; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). May play a minor role in the splicing of cellular pre-mRNAs (128 aa)
     
  0.998
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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