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AT1G05440 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G05440" - C-8 sterol isomerase in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G05440C-8 sterol isomerase (384 aa)    
Predicted Functional Partners:
TCP1
Transcription factor TCP1; Involved in petal morphogenesis (359 aa)
           
  0.732
DWF5
DWARF 5; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). Lesions in the gene coding for the enzyme cause dwarfism (432 aa)
     
   
  0.677
SYP111
Syntaxin of plants 111; Involved in cytokinesis. Acts as a cell plate-specific syntaxin, required for the fusion of vesicles at the plane of cell division (310 aa)
     
        0.621
AT3G51280
Tetratricopeptide repeat domain-containing protein; Probably involved in the regulation of cell division (430 aa)
     
        0.579
BIA1
BRASSINOSTEROID INACTIVATOR1 (435 aa)
           
  0.559
TOPII
Topoisomerase II; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1473 aa)
     
        0.535
CYCA1;1
Cyclin A1;1 (460 aa)
     
        0.527
AT1G65710
Uncharacterized protein (455 aa)
     
        0.510
AT4G31910
BR-related AcylTransferase1 (458 aa)
           
  0.507
HIK
HINKEL; Probable plus end-directed motor protein that functions in a MAP kinase signaling pathway (ANP1-MKK6-MPK4), which is essential for somatic cell cytokinesis, especially for the cell- plate formation and its expansion. Regulates the activity and the localization of ANP1, probably by association through the non- catalytic region of the kinase. Functionally redundant with NACK2 and essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during microgametogenesis and megagametogenesis (974 aa)
     
        0.505
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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