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ATX2 protein (Arabidopsis thaliana) - STRING interaction network
"ATX2" - Trithorax-like protein 2 in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ATX2Trithorax-like protein 2; Histone methyltransferase (1083 aa)    
Predicted Functional Partners:
TRO
TRAUCO; Trithorax-group gene homolog required for early embryogenesis (PubMed-20118203, PubMed-21423667). Required for the expression of FLC and FLC homologs and represses flowering (PubMed-21423667). Required for proper leaf growth and development (PubMed-21423667). Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 ’Lys-4’ (PubMed-21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed-21423667) (509 aa)
     
 
  0.958
AT3G21060
RbBP5 LIKE; Promotes the expression of FLC and FLC homologs to repress the floral transition (547 aa)
     
 
  0.957
HAG4
Histone acetyltransferase MYST1; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates ’Lys-5’ of histone H4 (H4K5ac) (PubMed-17877703, PubMed-19040736, PubMed-22170978, PubMed-23273925). Essential for gametophyte development (PubMed-19040736). Involved in DNA repair after UV-B exposure (PubMed-22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed-23273925) (445 aa)
     
 
  0.948
HAG5
MYST-like histone acetyltransferase 2; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates ’Lys-5’ of histone H4 (H4K5ac) (PubMed-16648464, PubMed-17877703). Essential for gametophyte development (PubMed-19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed-23273925) (445 aa)
     
 
  0.948
AT5G66240
transducin/WD40 domain-containing protein (331 aa)
     
 
  0.929
AT5G14530
transducin/WD40 domain-containing protein (330 aa)
       
 
  0.922
WDR5a
WD40 domain-containing protein; Forms multiple COMPASS-like complexes involved in histone methylation by interacting with different histone H3 ’Lys- 4’ methyltransferases such as ATX1, SDG14 or SDG16 (PubMed-21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed-19567704). Upregulates FLC and MAF4 expression to delay flowering (PubMed-19567704) (317 aa)
     
 
  0.906
TPL
TOPLESS; Transcriptional corepressor. May repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole during the transition stage of embryogenesis. Regulates the expression of PLT1 and PLT2. Negative regulator of jasmonate responses. Negative regulator of auxin responses. Negative regulator of multiple floral organ identity genes (PubMed-23034631). Required for ovule development (PubMed-25378179) (1131 aa)
     
 
  0.881
WDR5b
Human WDR5 (WD40 repeat) homolog b (333 aa)
     
 
  0.876
LUG
LEUNIG; Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development (PubMed-11782418, PubMed-15277686, PubMed-7743940). Implicated in embryo and floral development (PubMed-18390806). Involved in post- synthesis cell wal [...] (969 aa)
     
 
  0.874
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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