STRINGSTRING
ARI12 protein (Arabidopsis thaliana) - STRING interaction network
"ARI12" - ARIADNE 12 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARI12ARIADNE 12; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin- conjugating enzymes and then transfers it to substrates (496 aa)    
Predicted Functional Partners:
AT4G01020
Zinc finger-related and helicase and IBR domain-containing protein (1787 aa)
       
 
  0.987
NHL8
NDR1/HIN1-like 8 (688 aa)
           
  0.961
AT5G10370
Helicase , IBR and zinc finger protein domain-containing protein (1775 aa)
       
 
  0.929
AT5G60250
C3H4 type zinc finger protein (655 aa)
           
  0.739
VAP27-1
Vesicle associated protein; Part of a membrane-cytoskeletal adapter complex that forms a bridge between the endoplasmic reticulum and the plasma membrane. Associates with microtubules (256 aa)
     
   
  0.650
SWEETIE
SWEETIE (2223 aa)
       
      0.590
At1g49670
ARP protein (652 aa)
       
 
  0.490
RBR1
Retinoblastoma-related 1; Key regulator of entry into cell division. Acts as a transcription repressor of E2F target genes, whose activity is required for progress from the G1 to the S phase of the cell cycle. Hyperphosphorylation by CDKA-1 prevents the binding to E2F transcription factors, allowing G1 to S phase transition to operate (PubMed-18064404, PubMed-21444209). Forms a stable complex with E2FA that functions in maintaining cell proliferation through repression of cell differentiation (PubMed-22307083). Plays a central role in the mechanism controlling meristem cell differentia [...] (1013 aa)
           
  0.474
RGLG4
RING DOMAIN LIGASE 4 (401 aa)
           
  0.449
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (25%) [HD]