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ARI5 protein (Arabidopsis thaliana) - STRING interaction network
"ARI5" - Probable E3 ubiquitin-protein ligase ARI5 in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
ARI5Probable E3 ubiquitin-protein ligase ARI5; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin- conjugating enzymes and then transfers it to substrates (594 aa)    
Predicted Functional Partners:
Proline-rich spliceosome-associated (PSP) family protein; Involved in mRNA processing; Located in nucleus, chloroplast; Contains the following InterPro domains- PSP, proline-rich (InterPro-IPR006568), Protein of unknown function DUF382 (InterPro-IPR007180); BEST Arabidopsis thaliana protein match is- pliceosome associated protein-related (TAIR-AT1G11520.1) (598 aa)
E3 ubiquitin-protein ligase CIP8; Encodes a RING-H2 protein that interacts with the RING finger domain of COP1. CIP8 exhibits a strong interaction with the E2 ubiquitin conjugating enzyme AtUBC8 through its N-terminal domain and promotes ubiquitination in an E2-dependent fashion in vitro. It is possible that the AtUBC8-CIP8 module might interact with COP1 in vivo, thereby participating in proteasome-mediated degradation of HY5 (334 aa)
E3 ubiquitin-protein ligase PRT6; Ubiquitin ligase protein which is a component of the N- end rule pathway with the arginyltransferases ATE1 and ATE2. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Does not participate in degradation of proteins with N-terminal Phe or Leu. The N-end rule pathway regulates seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination. The end-rule pathway re [...] (2006 aa)
Zinc finger protein-like protein; RING/U-box superfamily protein; Its function is described as zinc ion binding; Expressed in egg cell; Contains the following InterPro domains- Zinc finger, C6HC-type (InterPro-IPR002867), Zinc finger, RING-type (InterPro-IPR001841); BEST Arabidopsis thaliana protein match is- RING/U-box superfamily protein (TAIR-AT3G53690.1); Has 3093 Blast hits to 3074 proteins in 222 species- Archae - 0; Bacteria - 0; Metazoa - 1283; Fungi - 653; Plants - 677; Viruses - 1; Other Eukaryotes - 479 (source- NCBI BLink) (303 aa)
DWNN domain, a CCHC-type zinc finger; Its function is described as zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in nucleus; Expressed in 25 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- DWNN domain (InterPro-IPR014891), Zinc finger, RING-type (InterPro-IPR001841), Zinc finger, CCHC-type (InterPro-IPR001878); BEST Arabidopsis thaliana protein match is- DWNN domain, a CCHC-type zinc finger (TAIR-AT4G17410.1); Has 13590 Blast hits to 9527 proteins in 457 species- Archae - 2; Bacteria - 408; Metazoa [...] (892 aa)
E3 ubiquitin-protein ligase UPL5; E3 ubiquitin protein ligase that regulates leaf senescence through ubiquitination and subsequent degradation of WRKY53 (873 aa)
Ubiquitin-conjugating enzyme E2 22; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins; Belongs to the ubiquitin-conjugating enzyme family (251 aa)
Ubiquitin-conjugating enzyme E2 27; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins; Belongs to the ubiquitin-conjugating enzyme family (203 aa)
E3 ubiquitin ligase PARAQUAT TOLERANCE 3; E3 ubiquitin ligase acting as a negative regulator of oxidative stress tolerance, probably by mediating 26S proteasome- mediated degradation of PRMT13/PRMT4B, thus preventing APX1 and GPX1 accumulation via the reduction of histone H3 methylation (H3R17me2a). Confers sensitivity to cadmium CdCl(2) and salt NaCl stresses (827 aa)
Uncharacterized protein F27G20.5; Encodes a protein whose sequence is similar to tobacco hairpin-induced gene (HIN1) and Arabidopsis non-race specific disease resistance gene (NDR1). Expression is not detected under normal conditions and in response to cucumber mosaic virus or spermine (688 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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