ORA59 protein (Arabidopsis thaliana) - STRING interaction network
"ORA59" - Octadecanoid-responsive Arabidopsis AP2/ERF 59 in Arabidopsis thaliana
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
ORA59Octadecanoid-responsive Arabidopsis AP2/ERF 59; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Acts as an essential integrator of the JA and ethylene signal transduction pathways. Activates the expression of the PDF1.2A gene (244 aa)    
Predicted Functional Partners:
Plant defensin 1.2; Confers broad-spectrum resistance to pathogens. Has antifungal activity in vitro (80 aa)
PHYTOCHROME AND FLOWERING TIME 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Positive regulator of shade avoidance and of ja [...] (836 aa)
Transcription factor MYC2; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA- dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5’-CACATG-3’), and to the G-box (5’-CACNTG-3’) and Z-box (5’-ATACGTGT-3’) of promoters. Binds directly to the pro [...] (623 aa)
APETALA 2; Probable transcriptional activator that promotes early floral meristem identity (PubMed-7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed-1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed-1675158, PubMed-23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in associ [...] (432 aa)
Auxin-responsive GH3 family protein (581 aa)
CORONATINE INSENSITIVE 1; Required for jasmonate-regulated plant fertility and defense processes, and for coronatine and/or other elicitors perceptions/responses. Seems to not be required for meiosis. Required for the regulation of some genes induced by wounding, but not for all. Component of SCF(COI1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including the ribulose bisphosphate carboxylase small chain 1B RBCS-1B and the histone deacetylase HDA6). These SCF complexes play crucial roles in regu [...] (592 aa)
Vegetative storage protein 2; May function as somatic storage protein during early seedling development (265 aa)
GATA transcription factor 25; Transcriptional activator that specifically binds 5’- GATA-3’ or 5’-GAT-3’ motifs within gene promoters (317 aa)
ETHYLENE RESPONSE 1; Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling (PubMed-15466228, PubMed-15703053). In the presence of ethylene, the auto-kinase activity of ETR1 is inhibited and the non-phosphorylated kinase domain binds tightly to the corresponding domain of EIN2 (PubMed-20591837) (738 aa)
Calmodulin binding protein 25; Calmodulin-binding protein that functions as a negative regulator of osmotic stress tolerance (238 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]