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DRIP1 protein (Arabidopsis thaliana) - STRING interaction network
"DRIP1" - DREB2A-interacting protein 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DRIP1DREB2A-interacting protein 1; E3 ubiquitin-protein ligase that acts as a negative regulator of the response to water stress. Mediates ubiquitination and subsequent proteasomal degradation of the drought-induced transcriptional activator DREB2A. Functionally redundant with DRIP2 (421 aa)    
Predicted Functional Partners:
RING1A
RING 1A (525 aa)
       
 
  0.972
RING1B
RING 1B; Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation (468 aa)
       
 
0.951
DREB2A
DRE-binding protein 2A; Transcriptional activator that binds specifically to the DNA sequence 5’-[AG]CCGAC-3’. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (335 aa)
       
 
  0.788
UBC8
Ubiquitin conjugating enzyme 8; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins (149 aa)
       
 
  0.725
UBC35
Ubiquitin-conjugating enzyme 35; Catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through ’Lys-63’. This type of poly- ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Required for postreplication repair of UV-damaged DNA and for adapting root developmental programs to suboptimal availability of iron (154 aa)
       
 
  0.697
FUS9
FUSCA 9; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis- promoting factors such as HY5, HYH and LAF1. Although strongly related to ubiquitin-conjugating enzyme, it has no catalytic activity by itself due to the absence of the conserved Cys active site at position 120. It can howev [...] (182 aa)
       
 
  0.688
SKP1
S phase kinase-associated protein 1; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F- box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F- box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(A [...] (160 aa)
       
 
  0.682
SK21
SKP1-like 21; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F- box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F- box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity) (351 aa)
     
      0.671
UBC30
Ubiquitin-conjugating enzyme 30; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (148 aa)
       
      0.671
UBC10
Ubiquitin-conjugating enzyme 10; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins (148 aa)
       
      0.671
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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