| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AT1G07330 | AT2G28390 | AT1G07330.1 | AT2G28390.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Vacuolar fusion protein MON1 homolog; Plays an important role in membrane trafficking through the secretory apparatus. In complex with CCZ1, acts as a guanine exchange factor (GEF) for RABG3F of the Rab7 protein family. Promotes the exchange of GDP to GTP, converting RABG3F from an inactive GDP-bound form into an active GTP-bound form. The RABG3F active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles. May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation | 0.521 |
| AT1G07330 | AT4G12770 | AT1G07330.1 | AT4G12770.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Chaperone DnaJ-domain superfamily protein; Promotes probably uncoating of clathrin-coated vesicles | 0.463 |
| AT1G07330 | AT5G56480 | AT1G07330.1 | AT5G56480.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein; Its function is described as lipid binding; Involved in lipid transport; Located in endomembrane system; Expressed in central cell; Contains the following InterPro domains- Bifunctional inhibitor/plant lipid transfer protein/seed storage (InterPro-IPR016140), Plant lipid transfer protein/seed storage/trypsin-alpha amylase inhibitor (InterPro-IPR003612); BEST Arabidopsis thaliana protein match is- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein (TAIR-AT1G3 [...] | 0.463 |
| AT1G07330 | CBL3 | AT1G07330.1 | AT4G26570.2 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Calcineurin B-like protein 3; Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binds calcium ions. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Negatively regulates the enzyme activity of MTN1 in the presence of calcium; Belongs to the calcineurin regulatory subunit family | 0.568 |
| AT1G07330 | CIPK23 | AT1G07330.1 | AT1G30270.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | 0.463 |
| AT1G07330 | CNGC1 | AT1G07330.1 | AT5G53130.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Cyclic nucleotide-gated ion channel 1; Acts as cyclic nucleotide-gated ion channel. Can be activated by cyclic AMP which leads to an opening of the cation channel. May be responsible for cAMP-induced calcium entry in cells and thus should be involved in the calcium signal transduction. Could transport K(+), Na(+) and Pb(2+) | 0.555 |
| AT1G07330 | CNGC11 | AT1G07330.1 | AT2G46440.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Cyclic nucleotide-gated ion channel 11; Member of Cyclic nucleotide gated channel family. Positive regulator of resistance against avirulent fungal pathogen; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family | 0.521 |
| AT1G07330 | CNGC14 | AT1G07330.1 | AT2G24610.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Probable cyclic nucleotide-gated ion channel 14; Member of Cyclic nucleotide gated channel family; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family | 0.642 |
| AT1G07330 | RAB7B | AT1G07330.1 | AT3G18820.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Ras-related protein RABG3f; Essential for trafficking from prevacuolar compartments to vacuoles. Involved in the trafficking of newly synthesized protein to vacuoles. Essential for plant growth. Participates in the recruitment of the core retromer components to the endosomal membrane by interacting with VPS35A | 0.624 |
| AT1G07330 | SKD1 | AT1G07330.1 | AT2G27600.1 | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1; Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex. May also regulate cell cycle. Required during seed development for the formation of mucilage in seed coat and testa. Involved in the maintenance of Na(+)/K(+) homeostasis under salt stress. Required for cell expansion | 0.554 |
| AT2G28390 | AT1G07330 | AT2G28390.1 | AT1G07330.1 | Vacuolar fusion protein MON1 homolog; Plays an important role in membrane trafficking through the secretory apparatus. In complex with CCZ1, acts as a guanine exchange factor (GEF) for RABG3F of the Rab7 protein family. Promotes the exchange of GDP to GTP, converting RABG3F from an inactive GDP-bound form into an active GTP-bound form. The RABG3F active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles. May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | 0.521 |
| AT2G28390 | CIPK23 | AT2G28390.1 | AT1G30270.1 | Vacuolar fusion protein MON1 homolog; Plays an important role in membrane trafficking through the secretory apparatus. In complex with CCZ1, acts as a guanine exchange factor (GEF) for RABG3F of the Rab7 protein family. Promotes the exchange of GDP to GTP, converting RABG3F from an inactive GDP-bound form into an active GTP-bound form. The RABG3F active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles. May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | 0.514 |
| AT2G28390 | RAB7B | AT2G28390.1 | AT3G18820.1 | Vacuolar fusion protein MON1 homolog; Plays an important role in membrane trafficking through the secretory apparatus. In complex with CCZ1, acts as a guanine exchange factor (GEF) for RABG3F of the Rab7 protein family. Promotes the exchange of GDP to GTP, converting RABG3F from an inactive GDP-bound form into an active GTP-bound form. The RABG3F active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles. May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation | Ras-related protein RABG3f; Essential for trafficking from prevacuolar compartments to vacuoles. Involved in the trafficking of newly synthesized protein to vacuoles. Essential for plant growth. Participates in the recruitment of the core retromer components to the endosomal membrane by interacting with VPS35A | 0.995 |
| AT4G12770 | AT1G07330 | AT4G12770.1 | AT1G07330.1 | Chaperone DnaJ-domain superfamily protein; Promotes probably uncoating of clathrin-coated vesicles | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | 0.463 |
| AT5G56480 | AT1G07330 | AT5G56480.1 | AT1G07330.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein; Its function is described as lipid binding; Involved in lipid transport; Located in endomembrane system; Expressed in central cell; Contains the following InterPro domains- Bifunctional inhibitor/plant lipid transfer protein/seed storage (InterPro-IPR016140), Plant lipid transfer protein/seed storage/trypsin-alpha amylase inhibitor (InterPro-IPR003612); BEST Arabidopsis thaliana protein match is- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein (TAIR-AT1G3 [...] | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | 0.463 |
| CBL3 | AT1G07330 | AT4G26570.2 | AT1G07330.1 | Calcineurin B-like protein 3; Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binds calcium ions. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Negatively regulates the enzyme activity of MTN1 in the presence of calcium; Belongs to the calcineurin regulatory subunit family | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | 0.568 |
| CBL3 | CIPK23 | AT4G26570.2 | AT1G30270.1 | Calcineurin B-like protein 3; Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binds calcium ions. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Negatively regulates the enzyme activity of MTN1 in the presence of calcium; Belongs to the calcineurin regulatory subunit family | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | 0.954 |
| CIPK23 | AT1G07330 | AT1G30270.1 | AT1G07330.1 | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | Dentin sialophosphoprotein; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G29620.1); Has 597 Blast hits to 536 proteins in 121 species- Archae - 2; Bacteria - 47; Metazoa - 170; Fungi - 43; Plants - 98; Viruses - 0; Other Eukaryotes - 237 (source- NCBI BLink) | 0.463 |
| CIPK23 | AT2G28390 | AT1G30270.1 | AT2G28390.1 | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | Vacuolar fusion protein MON1 homolog; Plays an important role in membrane trafficking through the secretory apparatus. In complex with CCZ1, acts as a guanine exchange factor (GEF) for RABG3F of the Rab7 protein family. Promotes the exchange of GDP to GTP, converting RABG3F from an inactive GDP-bound form into an active GTP-bound form. The RABG3F active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles. May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation | 0.514 |
| CIPK23 | CBL3 | AT1G30270.1 | AT4G26570.2 | CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium- dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it f [...] | Calcineurin B-like protein 3; Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binds calcium ions. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Negatively regulates the enzyme activity of MTN1 in the presence of calcium; Belongs to the calcineurin regulatory subunit family | 0.954 |
