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MAC5A protein (Arabidopsis thaliana) - STRING interaction network
"MAC5A" - CCCH-type zinc fingerfamily protein with RNA-binding domain in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MAC5ACCCH-type zinc fingerfamily protein with RNA-binding domain; Its function is described as RNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 25 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Zinc finger, CCCH-type (InterPro-IPR000571), RNA recognition motif, RNP-1 (InterPro-IPR000504), Nucleotide-binding, alpha-beta plait (InterPro-IPR012677); BEST Arabidopsis thaliana protein match is- CCCH-type zinc fingerfamily protein with [...] (481 aa)    
Predicted Functional Partners:
EMB14
Pre-mRNA-processing-splicing factor 8A; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex (By similarity). Required for embryo development (Ref.3). Required for splicing efficiency of COOLAIR introns and usage of the proximal poly(A) site. COOLAIR is a set of long non-coding antisense transcripts produced at the FLOWERING LOCUS C (FLC). COOLAIR initiates just downstream of the major sense transcript poly(A) site and terminates either early or extends into the FLC promoter region. S [...] (2359 aa)
     
  0.999
MOS4
Pre-mRNA-splicing factor SPF27 homolog; Encodes MOS4 (Modifier of snc1, 4), a nuclear protein homologous to human Breast Cancer-Amplified Sequence (BCAS2). MOS4 interacts with AtCDC5 and PRL1. All three proteins are essential for plant innate immunity (253 aa)
       
  0.999
emb1507
U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly (2171 aa)
     
  0.999
CDC5
Cell division cycle 5-like protein; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage; Belongs to the CEF1 family (844 aa)
     
  0.999
MAC3A
Pre-mRNA-processing factor 19 homolog 1; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity). Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity (523 aa)
     
  0.997
PRL1
Protein pleiotropic regulatory locus 1; Pleiotropic regulator of glucose, stress and hormone responses. Also regulates cytochrome P450 CYP90A1/CPD. Coordinates the expression of hormone- and stress-related genes and genes related to cell wall modification and growth, leading to altered sugar-dependent growth and developmental responses. Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. By suppressing the expression of several (1)O(2)- responsive genes, PRL1 seems to play a major rol [...] (486 aa)
     
  0.996
AT3G16650
Transducin/WD40 repeat-like superfamily protein; Pleiotropic regulator (479 aa)
     
  0.996
MAC3B
Pre-mRNA-processing factor 19 homolog 2; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity). Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity (525 aa)
     
  0.994
SKIP
SNW/SKI-interacting protein; Splicing factor involved in post-transcriptional regulation of circadian clock and flowering time genes. Associates with the pre-mRNA of PRR7, PRR9, ELF3 and GI, and is necessary for the regulation of their alternative splicing and mRNA maturation. Probably involved in splice site recognition; Belongs to the SNW family (613 aa)
     
  0.993
MEE5
Ribosomal protein S5/Elongation factor G/III/V family protein; Splicing factor involved in pre-mRNA splicing and component of the spliceosome. Essential for reproduction. In female gametophyte, is necessary for the egg cell and central cell fate determination and hence reproductive success. Involved in a mechanism that prevents accessory cells from adopting gametic cell fate. Is necessary to restrict LIS expression to interfere with egg-cell specification. Probable component of U5 small nuclear ribonucleoprotein (snRNP) that is required for pre-mRNA splicing. Plays an essential role in [...] (987 aa)
     
  0.993
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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