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AT1G07380 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G07380" - Neutral/alkaline non-lysosomal ceramidase in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G07380Neutral/alkaline non-lysosomal ceramidase (779 aa)    
Predicted Functional Partners:
SBH2
Sphingoid base hydroxylase 2; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2- amino-1,3,4-trihydroxyoctadecane and -eicosane) (259 aa)
         
  0.972
SBH1
Sphingoid base hydroxylase 1; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2- amino-1,3,4-trihydroxyoctadecane and -eicosane) (260 aa)
         
  0.972
ACD5
ACCELERATED CELL DEATH 5; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1- phosphate has a PCD suppressive effect. Thus, ceramide phosphor [...] (608 aa)
     
 
  0.954
ATCES1
Dihydroceramidase (255 aa)
           
  0.912
SPHK2
Sphingosine kinase 2; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various l sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4- hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-erythro-dihydrosphingosine, but has a very few activity toward D,L-threo- dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA that [...] (481 aa)
     
 
  0.904
AT5G49900
Beta-glucosidase, GBA2 type family protein; Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide (957 aa)
         
    0.900
TSC10B
TSC10B; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Is stereospecific for D-erythro-DHS production and does not produce L-threo-DHS (331 aa)
         
    0.900
AT4G10060
Beta-glucosidase, GBA2 type family protein; Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide (922 aa)
         
    0.900
DES-1-LIKE
Sphingolipid delta-4 desaturase; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides (332 aa)
         
    0.900
AT3G24180
Beta-glucosidase, GBA2 type family protein; Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide (950 aa)
         
    0.900
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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