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TRFL2 protein (Arabidopsis thaliana) - STRING interaction network
"TRFL2" - TRF-like 2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRFL2TRF-like 2; Binds specifically to the plant telomeric double- stranded DNA sequences. At least 6 repeats of telomeric sequences are required for binding (630 aa)    
Predicted Functional Partners:
TRFL5
TRF-like 5 (390 aa)
           
  0.861
TRFL10
TRF-like 10 (420 aa)
           
  0.806
AtPOT1b
Protection of telomeres 1b; Negatively regulates telomerase activity and participate in telomere end-protection. Does not bind single-stranded telomeric DNA (454 aa)
           
  0.731
KU70
KU70 homolog; Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU80, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase. Required for maintenance of the telomeric C-rich strand (621 aa)
       
 
  0.715
ATSAC1B
SUPPRESSOR OF ACTIN 1B; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Involved in priming for different defense responses (593 aa)
     
        0.438
AT5G61630
Uncharacterized protein (147 aa)
     
        0.438
CHX25
cation/H+ exchanger 25; May operate as a cation/H(+) antiporter (857 aa)
     
        0.438
AT5G53820
Late embryogenesis abundant protein (LEA) family protein (67 aa)
     
        0.438
AT5G39493
Self-incompatibility S1 family protein (132 aa)
     
        0.438
AT5G25550
Leucine-rich repeat (LRR) family protein; Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization (433 aa)
     
        0.438
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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