Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
TRF-like 2; Binds specifically to the plant telomeric double- stranded DNA sequences. At least 6 repeats of telomeric sequences are required for binding (630 aa)
Predicted Functional Partners:
TRF-like 5 (390 aa)
TRF-like 10 (420 aa)
Protection of telomeres 1b; Negatively regulates telomerase activity and participate in telomere end-protection. Does not bind single-stranded telomeric DNA (454 aa)
KU70 homolog; Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU80, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase. Required for maintenance of the telomeric C-rich strand (621 aa)
SUPPRESSOR OF ACTIN 1B; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Involved in priming for different defense responses (593 aa)
Uncharacterized protein (147 aa)
cation/H+ exchanger 25; May operate as a cation/H(+) antiporter (857 aa)
Late embryogenesis abundant protein (LEA) family protein (67 aa)
Self-incompatibility S1 family protein (132 aa)
Leucine-rich repeat (LRR) family protein; Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization (433 aa)
Your Current Organism:
NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress