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HDA08 protein (Arabidopsis thaliana) - STRING interaction network
"HDA08" - Histone deacetylase 8 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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HDA08Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (377 aa)    
Predicted Functional Partners:
hda17
Histone deacetylase 17; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (158 aa)
       
  0.977
AT2G46040
ARID/BRIGHT DNA-binding domain;ELM2 domain protein (562 aa)
       
 
  0.971
hda10
Histone deacetylase 10; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (142 aa)
       
  0.963
SUVR5
SU(VAR)3-9-RELATED protein 5; Histone methyltransferase that functions together with its binding partner LDL1/SWP1 as one of the regulators of flower timing in Arabidopsis (PubMed-17224141). Mediates H3K9me2 deposition and regulates gene expression in a DNA methylation- independent manner. Binds DNA through its zinc fingers and represses the expression of a subset of stimulus response genes. May represent a novel mechanism for plants to regulate their chromatin and transcriptional state, which may allow for the adaptability and modulation necessary to rapidly respond to environment or [...] (1382 aa)
   
  0.950
SRT2
Sirtuin 2; NAD-dependent protein deacylase. Catalyzes the NAD- dependent hydrolysis of acyl groups from lysine residues (By similarity). Negatively regulates plant basal defense against plant pathogens, possibly by suppressing salicylic acid biosynthesis (376 aa)
   
  0.911
SRT1
Sirtuin 1; NAD-dependent protein deacetylase. Has deacetylase activity towards H3K9Ac. May have a function in the safeguard against genome instabiliy and DNA damage to ensure plant cell growth (By similarity) (473 aa)
   
  0.906
HAG5
MYST-like histone acetyltransferase 2; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates ’Lys-5’ of histone H4 (H4K5ac) (PubMed-16648464, PubMed-17877703). Essential for gametophyte development (PubMed-19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed-23273925) (445 aa)
     
  0.903
HAG1
Histone acetyltransferase GCN5; Acetylates histone H3 and ADA2 proteins in vitro. Acetylates ’Lys-14’ of histone H3. Acetylation of histones gives a specific tag for epigenetic transcription activation. Operates in concert with certain DNA-binding transcriptional activators. Acts via the formation of large multiprotein complexes that modify the chromatin (By similarity) (568 aa)
     
  0.880
SUVH1
SU(VAR)3-9 homolog 1; Histone methyltransferase. Methylates ’Lys-9’ of histone H3. H3 ’Lys-9’ methylation represents a specific tag for epigenetic transcriptional repression (670 aa)
   
  0.849
HAF01
Transcription initiation factor TFIID subunit 1-A; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex (By similarity) (1919 aa)
     
  0.843
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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