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CPNIFS protein (Arabidopsis thaliana) - STRING interaction network
"CPNIFS" - Cysteine desulfurase 2 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CPNIFSCysteine desulfurase 2; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine (PubMed-12033984, PubMed-16455656). Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (PubMed-15480755, PubMed-17372218). Required for the maturation of all plastidic Fe-S proteins and, thus, essential for plant growth (PubMed-17372218) (463 aa)    
Predicted Functional Partners:
CPSUFE
SufE-like protein; Participates in cysteine desulfurization mediated by NFS2 in chloroplast and NIFS1 in mitochondrion (PubMed-16437155). Activates the cysteine desulfurase activity of NFS2 (PubMed-16455656). Cysteine desulfurization mobilizes sulfur from L-cysteine to yield L-alanine and supplies the inorganic sulfur for iron-sulfur (Fe-S) cluster formation. Glutaredoxins regulate SUFE1 activity by inducing its reduction and deglutathionylation (PubMed-24203231) (371 aa)
   
  0.999
QS
Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. Can complement nadA-deficient E.coli mutant. Essential for the de novo synthesis of NAD. Participates also in cysteine desulfurization mediated by NFS2. Can activate the cysteine desulfurase activity of NFS2 in vitro (718 aa)
   
  0.995
SUFE2
Sulfur E2; Participates in cysteine desulfurization mediated by NFS2. Can activate the cysteine desulfurase activity of NFS2 in vitro. Cysteine desulfurization mobilizes sulfur from L-cysteine to yield L-alanine and supplies the inorganic sulfur for iron- sulfur (Fe-S) cluster formation (258 aa)
   
  0.994
NAP7
Non-intrinsic ABC protein 7; Essential protein. Required during embryo development, especially at early stages. Involved in chloroplast differentiation (338 aa)
 
 
  0.980
ABCI7
Protein ABCI7 (475 aa)
 
  0.973
ABCI8
UPF0051 protein ABCI8; Involved in light signaling, probably by mediating the transport and correct distribution of protoporphyrin IX, a chlorophyll precursor, in response to far-red light (557 aa)
 
  0.971
MTO1
Cystathionine gamma-synthase; Catalyzes the first committed step of methionine (Met) biosynthesis. Catalyzes the formation of L-cystathionine from homoserine esters and L-cysteine, via a gamma-replacement reaction. Substrate preference for cystathionine synthesis is O- phospho-L-homoserine (OPH) > O(4)-succinyl-L-homoserine (OSH) >> O-acetyl-L-homoserine (OAH). Is able, at extremely low rate, to catalyze a gamma-elimination of OPH in the absence of cysteine to produce inorganic phosphate (Pi), 2-oxobutanoate and ammonia (563 aa)
   
 
  0.967
ABCI9
ATP-binding cassette I9 (470 aa)
 
  0.966
ISU1
SufE/NifU family protein; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed-15507320, PubMed-17417719). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3). In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the reci [...] (167 aa)
     
  0.963
AT1G33320
Putative cystathionine gamma-synthase; Catalyzes the first committed step of methionine (Met) biosynthesis. Catalyzes the formation of L-cystathionine from homoserine esters and L-cysteine, via a gamma-replacement reaction (412 aa)
   
 
  0.956
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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