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ALB1 protein (Arabidopsis thaliana) - STRING interaction network
"ALB1" - Magnesium-chelatase subunit ChlD, chloroplastic in Arabidopsis thaliana
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Predicted Interactions
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ALB1Magnesium-chelatase subunit ChlD, chloroplastic; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP- dependent chelation step. Does not bind abscisic acid; Belongs to the Mg-chelatase subunits D/I family (760 aa)    
Predicted Functional Partners:
GUN5
Magnesium-chelatase subunit ChlH, chloroplastic; Multifunctional protein involved in chlorophyll synthesis, plastid-to-nucleus retrograde signaling and abscisic acid (ABA) perception. In chlorophyll synthesis, catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. In addition to its function in the Mg-chelatase enzyme, is required for the plastid-to-nucleus retrograde signaling. The plastid-to-nucleus signal plays an important rol [...] (1381 aa)
 
 
  0.999
CHLM
Encodes a protein with methyltransferase activity responsible for the methylation of magnesium protoporphyrin IX. Mutants defective in this gene are affected in chlorophyll biosynthesis and show a reduction in the accumulation of a number of major thylakoid-associated proteins including components of PSI (LHCI), PSII (LHCII, D1, CP43) and the cytochrome b6f complex (Cytf). By contrast, no significant changes were detected for the proteins of the stroma and the chloroplast envelope; Belongs to the class I-like SAM-binding methyltransferase superfamily. Magnesium protoporphyrin O- methyl [...] (312 aa)
 
 
  0.999
PPOP1
Flavin containing amine oxidoreductase family; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX (537 aa)
   
 
  0.997
G4
UbiA prenyltransferase family protein; Encodes a protein with chlorophyll synthase activity. This enzyme has been shown to perform the esterification of chlorophyllide (a and b), the last step of chlorophyll biosynthesis. Although it can use either geranylgeranyl pyrophosphate (GGPP) or phytyl pyrophosphate (PhyPP) as substrates, the esterification reaction was faster with GGPP than with PhyPP (387 aa)
 
   
  0.995
CHLI1
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP- dependent chelation step. Possesses high affinity for ATP and may play a major role in chlorophyll biosynthesis. Does not bind abscisic acid (ABA), but is a positive regulator of ABA signaling (424 aa)
 
0.994
GUN4
Tetrapyrrole-binding protein, chloroplastic; GUN, genomes uncoupled, is necessary for coupling the expression of some nuclear genes to the functional state of the chloroplast. Binds to the magnesium chelatase complex and promotes formation of the substrate,a tetrapyrrole signaling molecule. Porphyrin-binding protein that enhances the activity of Mg-chelatase. Although required for chlorophyll accumulation under normal growth conditions, GUN4 is not essential for chlorophyll synthesis (265 aa)
     
   
  0.991
CHLI2
Magnesium-chelatase subunit ChlI-2, chloroplastic; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. Possesses low affinity for ATP and may play a limited role in chlorophyll biosynthesis, and contributes to the assembly of the Mg-chelatase complex (418 aa)
 
0.990
FC-I
Ferrochelatase-1, chloroplastic/mitochondrial; Catalyzes the last step of heme biosynthesis by inserting ferrous iron into protoporphyrin IX to produce protoheme. Produces heme for photosynthetic cytochromes, but does not seem to be involved in stress responses. May be involved in wound- induced supply of heme to defensive hemoproteins outside plastids. Regulates the expression of photosynthesis- associated nuclear genes in undevelopped chloroplasts through production of heme (466 aa)
   
 
  0.986
HEMC
Porphobilinogen deaminase, chloroplastic; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (382 aa)
   
   
  0.982
FC-II
Ferrochelatase-2, chloroplastic; Catalyzes the last step of heme biosynthesis by inserting ferrous iron into protoporphyrin IX to produce protoheme. Produces heme for photosynthetic cytochromes, and for proteins involved in abiotic and biotic stress responses. May play a role in the quality control of individual chloroplasts during photo-oxidative stress through regulation of heme biosynthesis; Belongs to the ferrochelatase family (522 aa)
   
 
  0.981
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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