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BIP3 protein (Arabidopsis thaliana) - STRING interaction network
"BIP3" - Binding protein 3 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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BIP3Binding protein 3; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and the general transcription factors (By similarity) (675 aa)    
Predicted Functional Partners:
ATERDJ3B
DNAJ heat shock family protein; Regulates protein folding in the endoplasmic reticulum (ER) lumen. Forms a complex in the ER with SDF2 and MED37A/BIP1 which is required for the proper accumulation and function of the surface-exposed leucine-rich repeat receptor kinases EFR involved in pathogen-associated molecular pattern (PAMP) triggered immunity (346 aa)
 
  0.994
ATERDJ3A
DnaJ domain-containing protein; Regulates protein folding in the endoplasmic reticulum (ER) lumen. Functions probably as a co-molecular chaperone that is required for normal growth of pollen tubes under high-temperature stress (572 aa)
   
 
  0.984
BZIP28
Putative bZIP transcription factor; Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed-18156219, PubMed-18634751, PubMed-18849477, PubMed-20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed-20876872) (675 aa)
       
 
  0.978
P58IPK
Homolog of mamallian P58IPK; Plays an important positive role in viral symptom development and is required for viral multiplication and pathogenesis (482 aa)
   
  0.968
ATJ1
DnaJ homolog AtJ1 (atj); Have a continuous role in plant development probably in the structural organization of compartments (427 aa)
 
  0.966
MGE1
Mitochondrial GrpE 1; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (302 aa)
   
 
  0.962
EMB1241
Embryo defective 1241; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (326 aa)
   
 
  0.962
AR192
Unknown function; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (327 aa)
   
 
  0.962
AT1G36390
Co-chaperone grpE-like protein; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (279 aa)
   
 
  0.962
AT4G28480
DNAJ heat shock protein (348 aa)
 
  0.961
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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