STRINGSTRING
SR30 protein (Arabidopsis thaliana) - STRING interaction network
"SR30" - Splicing factor, arginine/serine-rich 1/9 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SR30Splicing factor, arginine/serine-rich 1/9; Regulatory splicing factor that modulates alternative splicing and gene expression in specific cell types. Autoregulates its own expression. Probably involved in intron recognition and spliceosome assembly (268 aa)    
Predicted Functional Partners:
SCL30A
SC35-like splicing factor 30A; Involved in intron recognition and spliceosome assembly. Binds probably to multiple 5’-GAAG-3’ repeats found in its third intron, suggesting autoregulation of alternative splicing (PubMed-22913769). May be necessary for accurate splicing of the 3’ region of introns (262 aa)
       
 
  0.999
SCL30
SC35-like splicing factor 30; Involved in intron recognition and spliceosome assembly (Probable). Probably active at the 5’ splice sites (262 aa)
     
 
  0.998
SCL28
SC35-like splicing factor 28; Involved in intron recognition and spliceosome assembly (Probable). Probably active at the 5’ splice sites (236 aa)
     
 
  0.998
U1-70K
Encodes U1 snRNP 70K; Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA (427 aa)
     
  0.996
SC35
Ortholog of human splicing factor SC35; Probably involved in intron recognition and spliceosome assembly, but not involved in alternative splicing regulation of the SCL33 intron (303 aa)
     
  0.994
U2B'
U2 small nuclear ribonucleoprotein B; Involved in nuclear pre-mRNA splicing (232 aa)
     
  0.990
AT2G43370
RNA-binding (RRM/RBD/RNP motifs) family protein; May facilitate 5’ splice site recognition in the minor spliceosome. May be involved in interactions with components of the major spliceosome bound to the pyrimidine tract of an upstream U2-type intron (333 aa)
     
  0.990
U1A
Spliceosomal protein U1A; Involved in nuclear pre-mRNA splicing (By similarity). Seems to not be involved in polyadenylation (250 aa)
     
  0.989
ATU2AF65A
Splicing factor U2af large subunit A; Necessary for the splicing of pre-mRNA (573 aa)
     
  0.988
SR45
Arginine/serine-rich 45; Involved in 5’ and 3’ splicing site selection of introns, and may bridge the 5’ and 3’ components of the spliceosome. Isoform 1 is required during flower petal development and isoform 2 is involved in root growth. Regulates negatively glucose and abscisic acid (ABA) signaling during early seedling development. Involved in the RNA-directed DNA methylation pathway (PubMed-22274613) (425 aa)
         
  0.985
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (8%) [HD]