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ACLA-3 protein (Arabidopsis thaliana) - STRING interaction network
"ACLA-3" - ATP-citrate synthase alpha chain protein 3 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACLA-3ATP-citrate synthase alpha chain protein 3; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives. May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids. Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds. In contrast to all known anima [...] (424 aa)    
Predicted Functional Partners:
ACLB-1
ATP-citrate synthase beta chain protein 1; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives. May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids. Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds. In contrast to all known animal [...] (608 aa)
 
 
  0.994
ACLB-2
ATP-citrate synthase beta chain protein 2; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives. May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids. Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds. n contrast to all known animal [...] (608 aa)
 
 
  0.990
AT5G08300
Succinate--CoA ligase [ADP-forming] subunit alpha-1, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate- level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (347 aa)
 
 
  0.988
ACC2
Acetyl-CoA carboxylase 2; Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways including fatty acid elongation (2355 aa)
     
 
  0.971
AT5G23250
Succinate--CoA ligase [ADP-forming] subunit alpha-2, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate- level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (341 aa)
 
 
  0.969
CSY2
Citrate synthase 2, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria (514 aa)
   
  0.961
ATCS
Encodes a mitochrondrion targeted citrate synthase, the first enzyme of the tricarboxylic acid cycle, catalyzing the condensation of acetyl-CoA and oxaloacetate, finally yielding citrate and CoA (474 aa)
   
  0.954
CSY3
Citrate synthase 3, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria (509 aa)
   
  0.950
CSY5
Citrate synthase 5 (CSY5); Its function is described as citrate (SI)-synthase activity, transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; Involved in cellular carbohydrate metabolic process, tricarboxylic acid cycle; Located in mitochondrion; Expressed in 8 plant structures; Expressed during M germinated pollen stage, 4 anthesis, 4 leaf senescence stage, petal differentiation and expansion stage; Contains the following InterPro domains- Citrate synthase-like, large alpha subdomain (InterPro-IPR016142), Citrate synthase, eukaryotic (InterPro-I [...] (464 aa)
   
  0.946
CSY1
Encodes a peroxisomal citrate synthase that is expressed in siliques and developing seeds; Belongs to the citrate synthase family (480 aa)
   
  0.946
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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