STRINGSTRING
Haspin protein (Arabidopsis thaliana) - STRING interaction network
Haspin-related gene in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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Experiments
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[Homology]
Score
HaspinHaspin-related gene (599 aa)    
Predicted Functional Partners:
AUR3
Ataurora3; Phosphorylates in vitro histone H3 at ’Ser-10’ and ’Ser- 28’, but not at ’Thr-3’ or ’Thr-11’. Colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle (288 aa)
     
 
  0.934
AT2G20635
ATP binding;protein kinases;protein serine/threonine kinases; Serine/threonine-protein kinase that performs 2 crucial functions during mitosis- it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore. Acts as a substrate for anaphase-promoting complex or cyclosome (APC/C). Necessary for ensuring proper chromosome segregation. Can regulate chromosome segregation in a kinetochore- independent manner. The BUB1-BUB3 complex plays a role in the inhibition of APC/C when spindle-as [...] (525 aa)
     
 
  0.912
AT5G05510
Mad3/BUB1 homology region 1 (471 aa)
     
 
  0.695
TUBG1
Gamma-tubulin; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (474 aa)
     
   
  0.672
RHS8
Root hair specific 8; Xyloglucan-specific galacturonosyltransferase that forms the beta-D-galactosyluronic acid-(1->2)-alpha-D-xylosyl linkage. Required for root hair development probably by providing important acidic xyloglucans (664 aa)
           
  0.672
SMC2
SMC2-1 (SMC2); Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis (1175 aa)
     
 
  0.644
TEL1
Terminal EAR1-like 1 (615 aa)
           
  0.600
EMB2656
EMBRYO DEFECTIVE 2656 (1051 aa)
     
        0.576
BUBR1
Checkpoint serine/threonine-protein kinase; Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions may be to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C (By similarity) (396 aa)
     
   
  0.573
NEK6
Serine/threonine-protein kinase Nek5; Involved in epidermal-cell morphogenesis in hypocotyls and roots. May act on the microtubule function. May have a secondary role in trichome branching (956 aa)
           
  0.558
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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