• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
CDC5 protein (Arabidopsis thaliana) - STRING interaction network
"CDC5" - Cell division cycle 5-like protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC5Cell division cycle 5-like protein; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage; Belongs to the CEF1 family (844 aa)    
Predicted Functional Partners:
MOS4
Pre-mRNA-splicing factor SPF27 homolog; Encodes MOS4 (Modifier of snc1, 4), a nuclear protein homologous to human Breast Cancer-Amplified Sequence (BCAS2). MOS4 interacts with AtCDC5 and PRL1. All three proteins are essential for plant innate immunity (253 aa)
     
  0.999
EMB14
Pre-mRNA-processing-splicing factor 8A; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex (By similarity). Required for embryo development (Ref.3). Required for splicing efficiency of COOLAIR introns and usage of the proximal poly(A) site. COOLAIR is a set of long non-coding antisense transcripts produced at the FLOWERING LOCUS C (FLC). COOLAIR initiates just downstream of the major sense transcript poly(A) site and terminates either early or extends into the FLC promoter region. S [...] (2359 aa)
     
  0.999
emb1507
U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly (2171 aa)
     
  0.999
SKIP
SNW/SKI-interacting protein; Splicing factor involved in post-transcriptional regulation of circadian clock and flowering time genes. Associates with the pre-mRNA of PRR7, PRR9, ELF3 and GI, and is necessary for the regulation of their alternative splicing and mRNA maturation. Probably involved in splice site recognition; Belongs to the SNW family (613 aa)
     
  0.999
MAC3A
Pre-mRNA-processing factor 19 homolog 1; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity). Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity (523 aa)
     
  0.999
AT5G28740
Tetratricopeptide repeat (TPR)-like superfamily protein; Its function is described as binding; Involved in RNA processing; Located in intracellular; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- RNA-processing protein, HAT helix (InterPro-IPR003107), Tetratricopeptide-like helical (InterPro-IPR011990), Tetratricopeptide repeat-containing (InterPro-IPR013026); BEST Arabidopsis thaliana protein match is- crooked neck protein, putative / cell cycle protein, putative (TAIR-AT5G45990.1); Has 2811 Blast hits to 1455 proteins in [...] (917 aa)
     
  0.999
PRL1
Protein pleiotropic regulatory locus 1; Pleiotropic regulator of glucose, stress and hormone responses. Also regulates cytochrome P450 CYP90A1/CPD. Coordinates the expression of hormone- and stress-related genes and genes related to cell wall modification and growth, leading to altered sugar-dependent growth and developmental responses. Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. By suppressing the expression of several (1)O(2)- responsive genes, PRL1 seems to play a major rol [...] (486 aa)
     
  0.999
AT5G64270
Splicing factor, putative; Its function is described as binding; Involved in mRNA processing; Located in chloroplast; Expressed in 26 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Armadillo-like helical (InterPro-IPR011989), Splicing factor 3B subunit 1 (InterPro-IPR015016), HEAT, type 2 (InterPro-IPR021133), Armadillo-type fold (InterPro-IPR016024); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source [...] (1269 aa)
     
  0.999
ATO
Splicing factor SF3a60 homolog; Encodes a protein with similarity to pre-mRNA splicing factor SF3a60 that is involved in gametic cell fate determination. Loss of function results in the ectopic expression of egg cell makers suggesting a role in restriction of gametic cell fate. Expressed strongly in gametophytes and weakly in sporophytes; Belongs to the SF3A3 family (504 aa)
     
  0.999
EMB2765
P-loop containing nucleoside triphosphate hydrolases superfamily protein; EMBRYO DEFECTIVE 2765 (EMB2765); Located in plasma membrane, chloroplast; Expressed in 24 plant structures; Expressed during 13 growth stages; BEST Arabidopsis thaliana protein match is- RNA helicase, putative (TAIR-AT5G47010.1); Has 4121 Blast hits to 3614 proteins in 689 species- Archae - 125; Bacteria - 655; Metazoa - 959; Fungi - 1056; Plants - 630; Viruses - 0; Other Eukaryotes - 696 (source- NCBI BLink) (1509 aa)
     
  0.999
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]